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Psilocin: Difference between revisions

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Add Pendell's corner (Gnosis)
Pendell's corner: verbatim (Gnosis, p. 28)
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{{PendellsCorner
{{PendellsCorner
| quote  = The mushroom carries the prodrug; the body carries the active. Psilocybin is dephosphorylated to psilocin within minutes of ingestion, and what crosses into the brain is the simpler molecule. The pathway is brief and reliable — a small mercy of pharmacology, that the chemistry on the way in is exactly what the genus expected.
| quote  = Psilocin is the psychoactive molecule. Psilocybin is dephosphorylated into psilocin in the body. Psilocin is 4-hydroxy-N,N-dimethyltryptamine, DMT with a hydroxyl group on the number 4 carbon atom of the indole ring. ... Things are falling into place, mushrooms into toadstools, a major neurotransmitter in-between.
| volume = Gnosis
| volume = Gnosis
| voice  = curated paraphrase — replace with verbatim passage
| page  = 28
}}
}}



Revision as of 23:27, 15 May 2026

Classic Psychedelic, Tryptamine
Psilocin

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Summary
Classes
Classic Psychedelic, Tryptamine
Common uses
Pharmacy
Pharmacology
Purported mechanism
5-HT2A agonist


Pendell's corner
Psilocin is the psychoactive molecule. Psilocybin is dephosphorylated into psilocin in the body. Psilocin is 4-hydroxy-N,N-dimethyltryptamine, DMT with a hydroxyl group on the number 4 carbon atom of the indole ring. ... Things are falling into place, mushrooms into toadstools, a major neurotransmitter in-between.
— Dale Pendell, Pharmako/Gnosis, p. 28