Bufo alvarius: Difference between revisions
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Pendell's corner: verbatim (Gnosis, p. 217) |
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| duration = ~15 min | | duration = ~15 min | ||
| mechanism = 5-MeO-DMT is a potent 5-HT1A agonist (greater than 5-HT2A). Distinct from N,N-DMT in producing a more unitive, less visual, often ego-dissolving experience. | | mechanism = 5-MeO-DMT is a potent 5-HT1A agonist (greater than 5-HT2A). Distinct from N,N-DMT in producing a more unitive, less visual, often ego-dissolving experience. | ||
| intro = ''Bufo alvarius'' is the only toad whose parotid-gland venom contains 5-MeO-DMT in psychoactively significant quantities. (The cane toad, ''Bufo marinus'', has bufotenine and cardiotoxic bufosteroids instead.) Native to the Sonoran Desert. The dried venom ("toad smoke") is one of the most powerful entheogens known | | intro = ''Bufo alvarius'' is the only toad whose parotid-gland venom contains 5-MeO-DMT in psychoactively significant quantities. (The cane toad, ''Bufo marinus'', has bufotenine and cardiotoxic bufosteroids instead.) Native to the Sonoran Desert. The dried venom ("toad smoke") is one of the most powerful entheogens known, onset in seconds, full peak in ~5 min, baseline restored within 15. | ||
| legal = 5-MeO-DMT is Schedule I in US (since 2011); the toad itself is protected in several southwestern states | | legal = 5-MeO-DMT is Schedule I in US (since 2011); the toad itself is protected in several southwestern states | ||
| seealso = [[5-MeO-DMT]], [[DMT]], [[Anadenanthera]] | | seealso = [[5-MeO-DMT]], [[DMT]], [[Anadenanthera]] | ||
Revision as of 03:16, 19 May 2026
Animal Medicine, Phantastica
Bufo alvarius
Sonoran Desert Toad, Colorado River Toad
Bufo alvarius is the only toad whose parotid-gland venom contains 5-MeO-DMT in psychoactively significant quantities. (The cane toad, Bufo marinus, has bufotenine and cardiotoxic bufosteroids instead.) Native to the Sonoran Desert. The dried venom ("toad smoke") is one of the most powerful entheogens known, onset in seconds, full peak in ~5 min, baseline restored within 15.
5-MeO-DMT, DMT, Anadenanthera
Experience
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Effects
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See also
References
Summary
Classes
Animal Medicine, Phantastica
Common uses
Visionary0
Pharmacy
Preparations
Parotid-gland venom expressed onto a glass plate, dried into a shellac-like resin, vaporized and inhaled
Pharmacology
Routes
Inhalation (vaporized)
Onset
Seconds
Duration
~15 min
Legal status
5-MeO-DMT is Schedule I in US (since 2011); the toad itself is protected in several southwestern states
Purported mechanism
5-MeO-DMT is a potent 5-HT1A agonist (greater than 5-HT2A). Distinct from N,N-DMT in producing a more unitive, less visual, often ego-dissolving experience.
“Pendell's corner
I wasn't looking forward to this. I'm not looking forward to this. I was tired. "Again?" I thought, "another ally?" I've never been big on the dating scene, but meeting an ally isn't even like dating, it's like dating with a trial marriage. You have to give yourself over to it.
— Dale Pendell, Pharmako/Gnosis, p. 217