Tizanidine: Difference between revisions
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MDElliottMD (talk | contribs) Dedupe migration per interface-claude 2026-05-20: Muscle Relaxants (CNS-acting) merged into canonical Muscle relaxants. Member retagged. |
MDElliottMD (talk | contribs) Tier 1 taxonomy consolidation: removed redundant Category:Muscle_Relaxants (canonical already present) |
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[[Category:Muscle relaxants]] | [[Category:Muscle relaxants]] | ||
Revision as of 17:02, 21 May 2026
Muscle relaxant
Tizanidine
Zanaflex
Experience
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Problems
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+ Add a problemTitration strategies
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Effects
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Interactions
Pharmacogenomic + mechanism interactions
Pharmacokinetic mechanismSubstrate / metabolism relationships from primary literature
FDA Drug Interactions Table: sensitive index substrate of CYP1A2.
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Clinical relevance: does this interaction matter in practice?trivialcritical
Mechanism description, if it needs work:
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Your own experience with this combination:
Experience (1 a little, 5 a lot)
Outcome (-100 worst, +100 best)
Inferred from pharmacokinetic dataMaterialised by the inference engine; provenance shown per row
Fluvoxamine inhibits CYP1A2 (inhibitor_strong, intensity 90); Tizanidine is a substrate_major of CYP1A2 (intensity 80). Derived: Tizanidine exposure raised.
Inferred via Enzyme:CYP1A2 (exposure raised)
Rate this interaction. Reports are anonymous and help curate the page.
Clinical relevance: does this interaction matter in practice?trivialcritical
Confidence in this inference: is the inferred magnitude sound?overstatedsound
Mechanism description, if it needs work:
Is this row worth surfacing?
Your own experience with this combination:
Experience (1 a little, 5 a lot)
Outcome (-100 worst, +100 best)
Patient experience
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Relevant anecdote
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Relevant Literature
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Summary
Classes
Muscle relaxant
Common uses
Pharmacy
Pharmacology
Purported mechanism
Alpha-2 adrenergic receptor agonist