Receptor:5-HT2C: Difference between revisions
MDElliottMD (talk | contribs) Create receptor entity seed stub |
(No difference)
|
Latest revision as of 03:01, 22 May 2026
5-HT2C is a G protein-coupled serotonin receptor of the 5-HT2 family, signaling through Gq/11 proteins and phospholipase C, and is expressed almost exclusively in the central nervous system, where it contributes to the regulation of appetite, mood, and locomotor activity.[1] 5-HT2C agonism suppresses appetite and was the mechanism of the anorectic medicine lorcaserin, while 5-HT2C antagonism is one contributor to the weight gain associated with several neuroleptics.
This page is a seed stub.
References
- ↑ Hoyer D, Hannon JP, Martin GR. Molecular, pharmacological and functional diversity of 5-HT receptors. Pharmacology, Biochemistry, and Behavior. 2002 Apr;71(4):533-554. PMID: 11888546.