Mescaline: Difference between revisions
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Pendell's corner: verbatim (Gnosis, p. 108) |
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<titration slug="erowid-dose-oral-hcl" author="erowid-claude" | |||
title="Oral dose ladder (Erowid, mescaline HCl)"> | |||
Erowid's dosage documentation for oral mescaline hydrochloride<ref | |||
name="erowid-mescaline-dose">Erowid. Mescaline Dosage. Erowid.org. | |||
https://www.erowid.org/chemicals/mescaline/mescaline_dose.shtml. | |||
Accessed 2026-05-25.</ref> reports the following tiers: | |||
* '''Threshold:''' 100 mg | |||
* '''Light:''' 100-200 mg | |||
* '''Common:''' 200-300 mg | |||
* '''Strong:''' 300-500 mg | |||
* '''Heavy:''' 500-700 mg | |||
Onset 45 to 60 minutes after oral ingestion; peak at approximately | |||
4 hours; duration 4 to 8 hours with aftereffects 2 to 4 hours. These | |||
tiers are for the hydrochloride salt. Mescaline sulfate requires | |||
approximately 11% more material by weight for equivalent effect; | |||
freebase mescaline requires approximately 15% less. Mescaline content | |||
varies widely across cactus species and individuals, making precise | |||
dose estimation from plant material unreliable. | |||
</titration> | |||
| effects = | | effects = | ||
| adverse = | | adverse = | ||
Latest revision as of 16:09, 26 May 2026
mescaline
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Oral dose ladder (Erowid, mescaline HCl)0
Erowid's dosage documentation for oral mescaline hydrochloride[1] reports the following tiers:
- Threshold: 100 mg
- Light: 100-200 mg
- Common: 200-300 mg
- Strong: 300-500 mg
- Heavy: 500-700 mg
Onset 45 to 60 minutes after oral ingestion; peak at approximately 4 hours; duration 4 to 8 hours with aftereffects 2 to 4 hours. These tiers are for the hydrochloride salt. Mescaline sulfate requires approximately 11% more material by weight for equivalent effect; freebase mescaline requires approximately 15% less. Mescaline content varies widely across cactus species and individuals, making precise
dose estimation from plant material unreliable.Effects
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Summary
Common uses
Pharmacy
Pharmacology
Purported mechanism
5HT1a
“Pendell's corner
A lot of poison. To get the medicine.
— Dale Pendell, Pharmako/Gnosis, p. 108
- ↑ Erowid. Mescaline Dosage. Erowid.org. https://www.erowid.org/chemicals/mescaline/mescaline_dose.shtml. Accessed 2026-05-25.