Fluoxetine

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SSRI, Anxiolytic, Antidepressant

Fluoxetine

Prozac

Fluoxetine was the first to be released of a long line of subsequent SSRIs. It is remarkable in its extremely long half life and relative lack of withdrawal syndrome. It can also be very useful it helping taper and terminate other SxRI medicines.

Experience

👥 No personal reports yet

⚕ 1 provider report · avg efficacy 40.0/100 · avg side-effect burden 40.0/100 · 150 patients managed total

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Problems

Anxiety disorders broadly, including panic attacks, social anxiety, as well as OCD, Depressive disorders, potentially PTSD

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Titration strategies

Start no higher than 10 mg for first dose! Participant may increase by 10 mg every 2-12 weeks, or never increase if they are satisfied with the 10 mg effect, up to a total of 40 mg to start.

Discussion (0)

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Effects

Anxiolysis👤 no reports yet⚕️ ~33% +67.0 (n=1)

Classically starting at 3-4 weeks and improving for another 8-12

Delayed ejaculation👤 no reports yet⚕️ ~80% +0.0 (n=1)

Mood enhancement👤 no reports yet⚕️ ~5% +67.0 (n=1)

Nausea👤 100% -50.0 (n=2)⚕️ ~33% -33.0 (n=1)

Common, often improves over 1-2 weeks.

Sexual dysfunction👤 100% -83.5 (n=2)⚕️ — -67.0 (n=1)

Frequent; can persist long-term.

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Monitoring

none required

Relevant anecdote

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Relevant Literature

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