Brexpiprazole
From Pharmacopedia
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Antipsychotic, Neuroleptic
Brexpiprazole
Rexulti
Experience
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Effects
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Interactions
Pharmacogenomic + mechanism interactions
Pharmacogenomic guideline recommendationsCPIC and Dutch Pharmacogenetics Working Group clinical guidelines
DPWG guideline: The Royal Dutch Pharmacists Association - Pharmacogenetics Working Group (DPWG) recommends to use half of the normal dose of brexpiprazole for poor metabolizers of CYP2D6.
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Clinical relevance: does this interaction matter in practice?trivialcritical
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Summary
Classes
Antipsychotic, Neuroleptic
Common uses
Pharmacy
Pharmacology
Purported mechanism
D2/5-HT1A partial agonist; 5-HT2A/alpha antagonist