5-MeO-DMT

Research material, Tryptamine, Classic Psychedelic

5-MeO-DMT

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Summary

Classes

Research material, Tryptamine, Classic Psychedelic

Pharmacy

Pharmacology

Purported mechanism

Potent 5-HT2A agonist; sigma-1 agonist

“Pendell's corner

The 5-methoxy is not DMT-with-an-extra-decoration. She is a different room — wider, whiter, less furnished, more thorough. The Sonoran toad makes her; the yopo snuff carries her; the synthetic crystal delivers her in a form that bypasses every previous safeguard the tradition had built around the dose.

— Dale Pendell, Pharmako/Gnosis
curated paraphrase — replace with verbatim passage