Salvinorin A

Dissociative

Salvinorin A

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Summary

Classes

Dissociative

Common uses

Pharmacy

Pharmacology

Purported mechanism

Kappa-opioid receptor agonist

“Pendell's corner

She has a chemistry no one expected. Not an alkaloid; not a tryptamine; not a phenethylamine — a neoclerodane diterpene, the only non-nitrogenous psychotropic of her order. The receptors she finds are the kappa opioids, the ones the medical literature had filed under 'dysphoria.' She is the molecule that made the textbook footnote into the chapter.

— Dale Pendell, Pharmako/Gnosis
curated paraphrase — replace with verbatim passage