Nutmeg
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Plant Med, Empathogenica
Nutmeg
Myristica fragrans. Mace (the fruit aril)
Nutmeg is the dried seed kernel of Myristica fragrans, a Moluccan tree of the Myristicaceae (same family as the South American DMT-source Virola). At psychoactive doses (a sizable spoonful or more), produces a slow onset of empathogenic/dreamy effects lasting well into the next day, often with heavy nausea — Pendell's "med-of-last-resort."
MDMA, MDA, Cinnamon
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References
Summary
Classes
Plant Med, Empathogenica
Common uses
Culinary spice0
Pharmacy
Starting dose
0.5–1 oz (10–30 g) ground for psychoactive effect; far smaller for culinary use
Preparations
Ground dried seed (nutmeg) or fruit aril (mace); occasionally infused
Pharmacology
Routes
Oral
Onset
Slow — 2–6 h
Duration
12–24 h or longer
Purported mechanism
Active oils are myristicin, elemicin, and safrole — phenethylamine precursors that may be aminated in vivo to MMDA, TMA, and MDA respectively (Shulgin's 'essential amphetamines' hypothesis).
“Pendell's corner
The drug-of-last-resort. Myself, I like nutmeg in eggnog.
— Dale Pendell, Pharmako/Dynamis, p. 199