Mescal Bean
Unchecked
Plant Medicine, Phantastica
Mescal Bean
Sophora secundiflora. Texas mountain laurel, frijolillo
The Mescal Bean is the seed of Sophora secundiflora, a small Fabaceae tree of the US southwest and northern Mexico. Caches in Texas rock shelters confirm continuous human use for at least 10,000 years. Likely predecessor to Peyote in the Plains Indian Red Bean Cult before mescaline was discovered; the name "mescal" was later transferred to peyote (with the unrelated agave). Cytisine is closely related to varenicline and has been used for smoking cessation.
Peyote, Varenicline
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References
Summary
Classes
Plant Medicine, Phantastica
Common uses
Ceremonial0
Pharmacy
Preparations
Bright red seeds, traditionally ingested or smoked. Highly toxic, narrow margin between active and lethal
Pharmacology
Routes
Oral
Purported mechanism
Active alkaloid is cytisine, a nicotinic acetylcholine receptor agonist. NOT a classical 5-HT2A psychedelic.