Mescaline

mescaline

Experience

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Problems

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Titration strategies

Oral dose ladder (Erowid, mescaline HCl)▲0▼×

Erowid's dosage documentation for oral mescaline hydrochloride reports the following tiers:

• Threshold: 100 mg
• Light: 100-200 mg
• Common: 200-300 mg
• Strong: 300-500 mg
• Heavy: 500-700 mg

Onset 45 to 60 minutes after oral ingestion; peak at approximately 4 hours; duration 4 to 8 hours with aftereffects 2 to 4 hours. These tiers are for the hydrochloride salt. Mescaline sulfate requires approximately 11% more material by weight for equivalent effect; freebase mescaline requires approximately 15% less. Mescaline content varies widely across cactus species and individuals, making precise

dose estimation from plant material unreliable.

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Effects

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Interactions

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Relevant Literature

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Summary

Common uses

Pharmacy

Pharmacology

Purported mechanism

5HT1a

“Pendell's corner

A lot of poison. To get the medicine.

— Dale Pendell, Pharmako/Gnosis, p. 108