Nutmeg
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Plant Med, Empathogenica
Nutmeg
Myristica fragrans. Mace (the fruit aril)
Nutmeg is the dried seed kernel of Myristica fragrans, a Moluccan tree of the Myristicaceae (same family as the South American DMT-source Virola). At psychoactive doses (a sizable spoonful or more), produces a slow onset of empathogenic/dreamy effects lasting well into the next day, often with heavy nausea, Pendell's "med-of-last-resort."
MDMA, MDA, Cinnamon
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References
Summary
Classes
Plant Med, Empathogenica
Common uses
Culinary spice0
Pharmacy
Starting dose
0.5–1 oz (10–30 g) ground for psychoactive effect; far smaller for culinary use
Preparations
Ground dried seed (nutmeg) or fruit aril (mace); occasionally infused
Pharmacology
Routes
Oral
Onset
Slow, 2–6 h
Duration
12–24 h or longer
Purported mechanism
Active oils are myristicin, elemicin, and safrole, phenethylamine precursors that may be aminated in vivo to MMDA, TMA, and MDA respectively (Shulgin's 'essential amphetamines' hypothesis).
“Pendell's corner
The drug-of-last-resort. Myself, I like nutmeg in eggnog.
— Dale Pendell, Pharmako/Dynamis, p. 199