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Nutmeg

From Pharmacopedia
Revision as of 21:43, 15 May 2026 by Maintenance script (talk | contribs) (Add Pendell's corner (Poeia))
Plant Medicine, Empathogenica
Nutmeg
Myristica fragrans. Mace (the fruit aril)
Nutmeg is the dried seed kernel of Myristica fragrans, a Moluccan tree of the Myristicaceae (same family as the South American DMT-source Virola). At psychoactive doses (a sizable spoonful or more), produces a slow onset of empathogenic/dreamy effects lasting well into the next day, often with heavy nausea — Pendell's "drug-of-last-resort."

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See also

MDMA, MDA, Cinnamon

References

Summary
Classes
Plant Medicine, Empathogenica
Common uses
Culinary spice0
Pharmacy
Starting dose
0.5–1 oz (10–30 g) ground for psychoactive effect; far smaller for culinary use
Preparations
Ground dried seed (nutmeg) or fruit aril (mace); occasionally infused
Pharmacology
Routes
Oral
Onset
Slow — 2–6 h
Duration
12–24 h or longer
Purported mechanism
Active oils are myristicin, elemicin, and safrole — phenethylamine precursors that may be aminated in vivo to MMDA, TMA, and MDA respectively (Shulgin's 'essential amphetamines' hypothesis).
Pendell's corner
Nutmeg was the spice the Dutch killed for. She is also a deliriant — sailors and prisoners have known her in the larger dose for as long as the larger dose has been imaginable. Myristicin is not pleasant; the experience is long, ungainly, sometimes nightmarish. She is the warning Ally — the one whose dose-response curve trains you to weigh.
— Dale Pendell, Pharmako/Poeia
curated paraphrase — replace with verbatim passage