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2C-E

Pending
From Pharmacopedia
Research material, Phenethylamine, Classic Psychedelic
2C-E

Experience

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Problems

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Titration strategies

Oral dose ladder (Erowid)0
Erowid's dosage documentation for oral 2C-E[1] reports the following tiers:
  • Threshold: 2-5 mg
  • Light: 5-10 mg
  • Common: 10-15 mg
  • Strong: 15-30 mg
  • Heavy: 25-40 mg

Onset 20 to 90 minutes after oral ingestion; duration 6 to 10 hours

with aftereffects 2 to 6 hours.
Insufflated dose ladder (Erowid, tentative)0
Insufflated tiers reported by Erowid:[1]
  • Threshold: 1 mg
  • Light: 1-3 mg
  • Common: 3-7 mg
  • Strong: 6-10 mg
  • Heavy: 10+ mg

Onset 1 to 10 minutes; duration 3 to 6 hours with aftereffects 2 to 6 hours. Insufflated doses are markedly lower than oral and onset is

substantially faster.

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Effects

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Interactions

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Relevant Literature

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Summary
Classes
Research material, Phenethylamine, Classic Psychedelic
Common uses
Pharmacy
Pharmacology
Purported mechanism
Potent 5-HT2A agonist
  1. 1.0 1.1 Erowid. 2C-E Dosage. Erowid.org. https://www.erowid.org/chemicals/2ce/2ce_dose.shtml. Accessed 2026-05-25.