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Research material, Tryptamine, Classic Psychedelic
4-HO-MET

Experience

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Titration strategies

Oral dose ladder (Erowid)0
Erowid's dosage documentation for oral 4-HO-MET[1] reports the following tiers:
  • Threshold: 2-8 mg
  • Light: 5-10 mg
  • Common: 8-15 mg
  • Strong: 10-20 mg
  • Heavy: 25+ mg

Insufflated doses are reported in a similar range (threshold 2-7 mg, light 5-10 mg, common 8-15 mg, strong 12-20 mg, heavy 20+ mg); onset via insufflation is more abrupt and duration shorter than oral route.

Onset and duration data are not specified by Erowid for this substance.

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Effects

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Interactions

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Relevant Literature

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Summary
Classes
Research material, Tryptamine, Classic Psychedelic
Common uses
Pharmacy
Pharmacology
Purported mechanism
5-HT2A agonist
  1. Erowid. 4-HO-MET Dosage. Erowid.org. https://www.erowid.org/chemicals/4_ho_met/4_ho_met_dose.shtml. Accessed 2026-05-25.