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Research material, Phenethylamine, Classic Psychedelic
DOC

Experience

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Problems

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Titration strategies

Oral dose ladder (Erowid)0
Erowid's dosage documentation for oral DOC[1] reports the following tiers (threshold not

characterized):

  • Light: 1.0-1.5 mg
  • Common: 1.5-2.5 mg
  • Strong: 2.5-5.0 mg
  • Heavy: 5.0+ mg

Onset 0.5 to 2.5 hours; duration 8 to 20 hours; aftereffects 6 to 12

hours.

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Effects

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Interactions

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Relevant Literature

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Summary
Classes
Research material, Phenethylamine, Classic Psychedelic
Common uses
Pharmacy
Pharmacology
Purported mechanism
5-HT2A agonist; long duration
  1. Erowid. DOC Dosage. Erowid.org. https://www.erowid.org/chemicals/doc/doc_dose.shtml. Accessed 2026-05-25.