Methoxetamine

Research material, Dissociative

Methoxetamine

Experience

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Problems

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Titration strategies

Multi-route dose ladders (Erowid, very tentative)▲0▼×

Erowid's dosage documentation for methoxetamine (MXE) is marked "very tentative" throughout and

notes that "doses reported by different users vary by a large amount."

Insufflated:

• Threshold: 5-20 mg; Light: 10-50 mg; Common: 20-60 mg; Strong: 25-100+ mg

Oral:

• Threshold: 8-20 mg; Light: 10-30 mg; Common: 40-60 mg; Strong: 50-100+ mg

Sublingual/buccal:

• Threshold: 5-10 mg; Light: 8-25 mg; Common: 15-50 mg; Strong: 40-100+ mg

Intramuscular:

• Threshold: 3-8 mg; Light: 5-20 mg; Common: 15-30 mg; Strong: 20-80+ mg

Timing data are not provided by Erowid. The wide variability between users (some report strong effects at 50 mg; others minimal at the same dose) and Erowid's tentative qualifier should be reflected in

any presentation.

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Effects

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Interactions

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Relevant Literature

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Summary

Classes

Research material, Dissociative

Common uses

Pharmacy

Pharmacology

Purported mechanism

NMDA antagonist; SERT inhibitor; sigma-1 agonist