Toggle menu
Toggle preferences menu
Toggle personal menu
Not logged in
Your IP address will be publicly visible if you make any edits.

Methoxetamine

Pending
From Pharmacopedia
Research material, Dissociative
Methoxetamine

Experience

👥 No personal reports yet
⚕ No clinical reports yet

Log in to add your own experience.

Problems

No problems yet. Be the first to suggest one.

+ Add a problem

Titration strategies

Multi-route dose ladders (Erowid, very tentative)0
Erowid's dosage documentation for methoxetamine (MXE)[1] is marked "very tentative" throughout and

notes that "doses reported by different users vary by a large amount."

Insufflated:

  • Threshold: 5-20 mg; Light: 10-50 mg; Common: 20-60 mg; Strong: 25-100+ mg

Oral:

  • Threshold: 8-20 mg; Light: 10-30 mg; Common: 40-60 mg; Strong: 50-100+ mg

Sublingual/buccal:

  • Threshold: 5-10 mg; Light: 8-25 mg; Common: 15-50 mg; Strong: 40-100+ mg

Intramuscular:

  • Threshold: 3-8 mg; Light: 5-20 mg; Common: 15-30 mg; Strong: 20-80+ mg

Timing data are not provided by Erowid. The wide variability between users (some report strong effects at 50 mg; others minimal at the same dose) and Erowid's tentative qualifier should be reflected in

any presentation.

+ Add a titration strategy

Effects

No effects listed yet. Be the first to suggest one.

+ Add an effect

Interactions

No interactions reported yet.

Relevant anecdote

No anecdotes yet. Share a relevant one.

+ Add an anecdote

Relevant Literature

No literature entries yet.

Log in to submit relevant literature.

Pharmacy
Common uses
Classification(s)
Classes
Research material, Dissociative
Pharmacology
Purported mechanism
NMDA antagonist; SERT inhibitor; sigma-1 agonist
Pharmacopedia is intended for reference. Nothing here is advice. In an emergency call 911; US Poison Control 1-800-222-1222. See the full disclaimer.
  1. ↑ Erowid. Methoxetamine Dosage. Erowid.org. https://www.erowid.org/chemicals/methoxetamine/methoxetamine_dose.shtml. Accessed 2026-05-26.