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Medicines > generic: Benazepril & fda max: 80 mg/d & bioavailability: ~37% (oral; food does not affect)'"`UNIQ--ref-00000A23-QINU`"'

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generic: (Click arrow to add another value)
brand:
Lotensin (1)
classes:
[[:Category:ACE_inhibitors|ACE inhibitor]] (1) · [[:Category:Antihypertensives|Antihypertensive]] (1)
mechanism:
'"`UNIQ--vote-00000A1D-QINU`"' Like other ACE inhibitors, it raises bradykinin (driving the dry cough and rare angioedema). Renally cleared; dose-adjust in renal impairment'"`UNIQ--ref-00000A1E-QINU`"'. (1)
uses:
'"`UNIQ--vote-00000A1F-QINU`"', '"`UNIQ--vote-00000A20-QINU`"', '"`UNIQ--vote-00000A21-QINU`"' (1)
starting dose:
10 mg PO once daily (5 mg if on a diuretic); titrate to 40 mg (1)
preparations:
5, 10, 20, 40 mg tablets (1)
fda max: (Click arrow to add another value)
routes:
Oral (1)
onset:
BP lowering within 1 hour; max at 6 hours (1)
duration:
24 hours (1)
halflife:
10-11 hours (benazeprilat, the active metabolite)'"`UNIQ--ref-00000A22-QINU`"' (1)
bioavailability: (Click arrow to add another value)
pregnancy:
'''Contraindicated in pregnancy''' (all trimesters); fetal renal injury, oligohydramnios, skull hypoplasia, hypotension. Stop on detection'"`UNIQ--ref-00000A24-QINU`"' (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)
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