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Medicines > classes : [[:Category:SGLT2_inhibitors|SGLT2 inhibitor]] or dissociative & fda max: 25 mg/d

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generic:
Empagliflozin (1)
brand:
Jardiance (1)
classes: (Click arrow to add another value)
mechanism:
None (1)
uses:
'"`UNIQ--vote-00000278-QINU`"', '"`UNIQ--vote-00000279-QINU`"', '"`UNIQ--vote-0000027A-QINU`"', '"`UNIQ--vote-0000027B-QINU`"' (1)
starting dose:
10 mg PO once daily in the morning; may titrate to 25 mg for additional glycemic effect (1)
preparations:
10 mg, 25 mg tablets (1)
fda max: (Click arrow to add another value)
routes:
Oral (1)
onset:
Glycosuria within hours; HbA1c effect at 12 weeks; cardiovascular and renal benefits over months (1)
duration:
24 hours (1)
halflife:
~12.4 hours'"`UNIQ--ref-0000027C-QINU`"' (1)
bioavailability:
High (oral; not affected by food, but typically given with the morning meal)'"`UNIQ--ref-0000027D-QINU`"' (1)
pregnancy:
Avoid in second and third trimesters; fetal SGLT2 inhibition disrupts kidney development.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)

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