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Medicines > classes : Androgen / Anabolic Steroid or Antidepressant & onset: Hours (transdermal); days (IM esters)

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generic:
Testosterone (1)
brand:
AndroGel, Testim, Axiron, Fortesta (gels); Androderm (patch); Aveed (IM); Striant (buccal); Natesto (nasal); Jatenzo, Tlando (oral undecanoate) (1)
classes: (Click arrow to add another value)
mechanism:
Endogenous androgen binding to androgen receptors; mediates male secondary sex characteristics, anabolism, libido, erythropoiesis, and CNS effects on mood/energy/aggression. Aromatized peripherally to estradiol; reduced to DHT. (1)
uses:
'"`UNIQ--vote-00000758-QINU`"', '"`UNIQ--vote-00000759-QINU`"', '"`UNIQ--vote-0000075A-QINU`"' (1)
starting dose:
Formulation-dependent. Gels: 40–50 mg topically daily. Cypionate/enanthate IM: 50–100 mg weekly. Undecanoate IM: 750 mg q10w. Patch: 4 mg/d. (1)
preparations:
Gels, patches, IM cypionate/enanthate/undecanoate, buccal tabs, nasal gel, oral undecanoate, subcutaneous pellets (1)
fda max:
Formulation-dependent (1)
routes:
buccal (1) · IM (1) · nasal (1) · oral (undecanoate only) (1) · Topical (gel/patch) (1)
onset: (Click arrow to add another value)
duration:
Hours (nasal); ~24 h (gel/patch); 1–2 weeks (cypionate/enanthate IM); ~10 weeks (undecanoate IM) (1)
halflife:
Highly variable by formulation; native T is hours (1)
bioavailability:
Oral non-undecanoate has essentially zero bioavailability (hepatic first-pass) (1)
pregnancy:
Category X, contraindicated; teratogenic (virilization of female fetus) (1)
legal:
Schedule III (DEA, US) (1)

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