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Drilldown: Medicines

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Medicines > classes : Anticonvulsant or Antidepressant or Phenethylamine

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generic:
brand:
None (26) · Anafranil (1) · Aptiom (1) · Aurorix (1) · Banzel (1) · Briviact (1) · Cerebyx (1) · Cymbalta, Drizalma Sprinkle, Irenka, Yentreve (1) · Depakote (1) · Diacomit (1) · Dilantin (1) · Edronax (1) · Epidiolex (1) · Felbatol (1) · Fetzima (1) · Fintepla (1) · Fycompa (1) · Gabitril (1) · Ludiomil (1) · Luminal (1) · Marplan (1) · Nardil (1) · Nexus, Eroxan (historical, late-1980s through mid-1990s) (1) · Norpramin (1) · Onfi (1) · Parnate (1) · Sabril (1) · Savella (1) · Serzone (1) · Stablon (1) · Surmontil (1) · Tofranil (1) · Valdoxan (1) · Vimpat (1) · Vivactil (1) · Xcopri (1) · Zarontin (1) · Zoloft (1) · Zonegran (1)
classes: (Click arrow to add another value)
mechanism:
5-HT2A agonist (12) · Potent 5-HT2A agonist (5) · Irreversible non-selective MAO inhibitor (3) · Selective norepinephrine reuptake inhibitor (3) · Serotonin and norepinephrine reuptake inhibitor (3) · Serotonin–norepinephrine reuptake inhibitor (2) · Sodium channel blocker (2)
uses:
None (63) · Depression, anxiety, neuropathic pain, fibromyalgia, chronic musculoskeletal pain (1)
starting dose:
None (63) · 25 mg (1)
preparations:
None (63) · 25 mg, 50 mg, 100 mg tablets; oral concentrate 20 mg/mL (1)
fda max:
None (63) · 200 mg/d (1)
routes:
None (61) · insufflated (1) · Oral (3) · PR (1)
onset:
None (61) · 45-75 min (oral) (1) · Anxiolysis classically 3-4 weeks, continuing improvement to 8-12 weeks (1) · Mood: 2–4 weeks. Pain: often within 1–2 weeks. (1)
duration:
None (61) · 4-8 h (1) · Chronic daily dosing (1) · Long (1)
halflife:
None (61) · Not well characterized (1) · ~12 hours (1) · ~26 h (sertraline; range 13-45 h, longer in females); ~62-104 h (N-desmethylsertraline, weakly active) (1)
bioavailability:
None (61) · Absolute bioavailability not precisely characterized; food modestly increases exposure (1) · Not well characterized (1) · ~50% (highly variable) (1)
pregnancy:
None (61) · Category C (1) · Category C'"`UNIQ--ref-0000008F-QINU`"' (1) · Not established (1)
legal:
None (61) · Rx-only (1) · Rx-only in US (1) · [[USLegal:DEA Schedule I|Schedule I]] (United States) (1)

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