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Medicines > classes : Anticonvulsant or Botanical or [[:Category:Analgesics|Non-opioid analgesic]]

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generic:
brand:
None (23) · Aptiom (1) · Banzel (1) · Briviact (1) · Cerebyx (1) · Depakote (1) · Diacomit (1) · Dilantin (1) · Epidiolex (1) · Felbatol (1) · Fintepla (1) · Fycompa (1) · Gabitril (1) · Luminal (1) · Onfi (1) · Sabril (1) · Tylenol, Panadol (international), Ofirmev (IV); huge OTC presence (1) · Vimpat (1) · Xcopri (1) · Zarontin (1) · Zonegran (1)
classes: (Click arrow to add another value)
mechanism:
Contains LSA (2) · Contains mescaline (2) · Sodium channel blocker (2)
uses:
None (42) · '"`UNIQ--vote-000006A2-QINU`"', '"`UNIQ--vote-000006A3-QINU`"', '"`UNIQ--vote-000006A4-QINU`"' (1)
starting dose:
None (42) · 325-1000 mg PO every 4-6 hours as needed; maximum 4 g/d in healthy adults, 3 g/d in regular users or hepatic risk; pediatric 10-15 mg/kg every 4-6 hours (1)
preparations:
None (42) · 325, 500, 650 mg tablets; 80, 160 mg chewables; 160 mg/5 mL pediatric liquid; 325 mg suppository; 1000 mg/100 mL IV (Ofirmev); fixed-dose combinations with opioids, decongestants, antihistamines (1)
fda max:
None (42) · 4 g/d in healthy adults; 3 g/d conservative limit; 2 g/d in cirrhosis or chronic alcohol use (1)
routes:
None (42) · IV (1) · Oral (1) · rectal (1)
onset:
None (42) · PO: 30-60 minutes; IV: minutes (1)
duration:
None (42) · 4-6 hours (1)
halflife:
None (42) · 1-3 hours (normal liver); markedly prolonged in overdose with glutathione depletion'"`UNIQ--ref-000006A5-QINU`"' (1)
bioavailability:
None (42) · ~85-98% (oral)'"`UNIQ--ref-000006A6-QINU`"' (1)
pregnancy:
None (42) · Long the preferred analgesic-antipyretic in pregnancy; recent observational studies have raised speculative neurodevelopmental signals that remain under investigation.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
None (42) · OTC and [[USLegal:Prescription only|Rx-only]] (IV, combination products) in US (1)

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