Drilldown: Medicines

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None (69) · Actos (1) · Amaryl (1) · Aptiom (1) · Banzel (1) · Briviact (1) · Cerebyx (1) · Delysid (historical, Sandoz, withdrawn 1965) (1) · Depakote (1) · Diacomit (1) · Dilantin (1) · Epidiolex (1) · Farxiga (US), Forxiga (international) (1) · Felbatol (1) · Fintepla (1) · Fycompa (1) · Gabitril (1) · Glucophage, Glucophage XR, Fortamet, Glumetza, Riomet (1) · Glucotrol, Glucotrol XL (1) · Januvia; with metformin Janumet/Janumet XR (1) · Jardiance (1) · Luminal (1) · Onfi (1) · Sabril (1) · Tradjenta; with metformin Jentadueto (1) · Vimpat (1) · Xcopri (1) · Zarontin (1) · Zonegran (1)

Research material · Classic Psychedelic · Stimulant · Opioid · Sedative-Hypnotic · Phenethylamine · Tryptamine · Benzodiazepine · Botanical · [[:Category:Antihypertensives|Antihypertensive]] · Dissociative · Anticonvulsant · Antidepressant · Plant Medicine · Analgesic · Antipsychotic · Antiparkinsonian · Empathogen · Neuroleptic · Cathinone

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5-HT2A agonist (26) · None (5) · Potent 5-HT2A agonist (5) · LSD analogue; 5-HT2A agonist (4) · Prodrug of LSD; 5-HT2A agonist (4) · Contains LSA (2) · Contains mescaline (2) · Sodium channel blocker (2)

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None (89) · '"`UNIQ--vote-00000015-QINU`"', '"`UNIQ--vote-00000016-QINU`"', '"`UNIQ--vote-00000017-QINU`"' (1) · '"`UNIQ--vote-00000278-QINU`"', '"`UNIQ--vote-00000279-QINU`"', '"`UNIQ--vote-0000027A-QINU`"', '"`UNIQ--vote-0000027B-QINU`"' (1) · '"`UNIQ--vote-000002D8-QINU`"' (1) · '"`UNIQ--vote-00000491-QINU`"' (1) · '"`UNIQ--vote-0000054E-QINU`"', '"`UNIQ--vote-0000054F-QINU`"', '"`UNIQ--vote-00000550-QINU`"', '"`UNIQ--vote-00000551-QINU`"' (1) · '"`UNIQ--vote-00000764-QINU`"' (1) · '"`UNIQ--vote-00000822-QINU`"', '"`UNIQ--vote-00000823-QINU`"' (1) · '"`UNIQ--vote-0000117B-QINU`"' (1)

None (89) · 1-2 mg PO once daily with breakfast; titrate by glycemic response (1) · 10 mg PO once daily in the morning; 5 mg starting in heart failure (1) · 10 mg PO once daily in the morning; may titrate to 25 mg for additional glycemic effect (1) · 100 mg PO once daily (50 mg if CrCl 30-44; 25 mg if <30 or dialysis) (1) · 15-30 mg PO once daily; titrate to 45 mg (1) · 5 mg PO once daily (no renal dose adjustment, unlike sitagliptin) (1) · 5 mg PO once daily, 30 minutes before breakfast; XL: 5 mg with breakfast (1) · 500 mg PO once or twice daily with meals; titrate weekly to limit GI effects (1)

None (89) · 1 mg, 2 mg, 4 mg tablets (1) · 10 mg, 25 mg tablets (1) · 15, 30, 45 mg tablets (1) · 25, 50, 100 mg tablets; combination tablets with metformin (1) · 5 mg tablets; combination with metformin (1) · 5 mg, 10 mg immediate-release tablets; 2.5 mg, 5 mg, 10 mg extended-release tablets (1) · 5 mg, 10 mg tablets (1) · 500 mg, 850 mg, 1000 mg IR tablets; 500 mg, 750 mg, 1000 mg ER tablets; 500 mg/5 mL oral solution (1)

None (89) · 10 mg/d (1) · 100 mg/d (1) · 25 mg/d (1) · 2550 mg/d (IR); 2000 mg/d (ER) (1) · 40 mg/d (IR; doses >15 mg given as divided BID); 20 mg/d (XL) (1) · 45 mg/d (1) · 5 mg/d (1) · 8 mg/d (1)

None (88) · Oral (9)

None (88) · 1-2 hours (1) · 30–60 minutes (1) · Glucose lowering within days; HbA1c effect at 8-12 weeks (1) · Glycosuria within hours; HbA1c effect at 12 weeks; cardiovascular and renal benefits over months (1) · Glycosuria within hours; HbA1c effect at 12 weeks; CV/renal benefits over months (1) · HbA1c effect at 12-16 weeks (slower than other classes) (1) · Postprandial glucose effect within days; HbA1c by 12 weeks (2) · Within 30 minutes (IR) (1)

None (88) · 24 hours (6) · 8–12 hours (1) · ~12 hours (IR); 24 hours (ER) (1) · ~12-24 hours (1)

None (88) · 2-5 hours'"`UNIQ--ref-000002D9-QINU`"' (1) · 3–5 hours (1) · 6.2 hours (plasma); ~17 hours in erythrocytes'"`UNIQ--ref-00000018-QINU`"' (1) · ~12 hours (effective); terminal much longer'"`UNIQ--ref-0000117C-QINU`"' (1) · ~12.4 hours'"`UNIQ--ref-0000027C-QINU`"' (1) · ~12.4 hours'"`UNIQ--ref-00000765-QINU`"' (1) · ~12.9 hours'"`UNIQ--ref-00000552-QINU`"' (1) · ~3-7 hours (parent); 16-24 hours including active metabolites'"`UNIQ--ref-00000824-QINU`"' (1) · ~5-9 hours (parent and active metabolites combined)'"`UNIQ--ref-00000492-QINU`"' (1)

None (88) · 50-60% (oral; decreased with food, but food given anyway for GI tolerance)'"`UNIQ--ref-00000019-QINU`"' (1) · 70–90% (oral) (1) · High (oral; absorption not affected by food)'"`UNIQ--ref-00000825-QINU`"' (1) · High (oral; not affected by food, but typically given with the morning meal)'"`UNIQ--ref-0000027D-QINU`"' (1) · ~100% (oral; food delays absorption, hence pre-meal dosing for IR)'"`UNIQ--ref-000002DA-QINU`"' (1) · ~100% (oral; not significantly affected by food)'"`UNIQ--ref-00000493-QINU`"' (1) · ~30% (oral)'"`UNIQ--ref-0000117D-QINU`"' (1) · ~78% (oral; high-fat meal modestly reduces but is not clinically significant)'"`UNIQ--ref-00000553-QINU`"' (1) · ~87% (oral)'"`UNIQ--ref-00000766-QINU`"' (1)

None (88) · Avoid in second and third trimesters; fetal SGLT2 inhibition disrupts kidney development.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (2) · Avoid; switch to insulin. Hypoglycemia in newborn reported.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1) · Avoid; switch to insulin. Neonatal hypoglycemia reported.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1) · Generally considered safe; widely used in PCOS and gestational diabetes; placental transfer occurs.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1) · Limited data; switch to insulin where feasible.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (3) · Not established (1)

None (88) · Schedule I (United States) (1) · [[USLegal:Prescription only|Rx-only]] in US (7) · [[USLegal:Prescription only|Rx-only]] in US. Carries a '''Boxed Warning''' for heart failure (do not initiate in NYHA III/IV; can precipitate or worsen HF in any patient)'"`UNIQ--ref-00000826-QINU`"' (1)