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Medicines (732)

Medicines > classes

: Antidepressant

or [[:Category:Antiarrhythmics|Antiarrhythmic (Vaughan-Williams class IC)]]

& routes: Oral

Use the filters below to narrow your results.

Duloxetine (1) · Flecainide (1) · Sertraline (1)

Cymbalta, Drizalma Sprinkle, Irenka, Yentreve (1) · Tambocor (US brand discontinued) (1) · Zoloft (1)

Serotonin–norepinephrine reuptake inhibition (balanced) (1) · TrkB/BDNF'"`UNIQ--ref-00000084-QINU`"' '"`UNIQ--vote-00000085-QINU`"' (1) · '"`UNIQ--vote-0000113A-QINU`"' Concomitant β-blocker or CCB is required when used for AF to prevent 1:1 atrial flutter conduction (flecainide can slow atrial rate to a level where AV conduction allows dangerous ventricular rates). CYP2D6 substrate'"`UNIQ--ref-0000113B-QINU`"'. (1)

None (1) · Depression, anxiety, neuropathic pain, fibromyalgia, chronic musculoskeletal pain (1) · '"`UNIQ--vote-0000113C-QINU`"', '"`UNIQ--vote-0000113D-QINU`"', '"`UNIQ--vote-0000113E-QINU`"' (1)

None (1) · 25 mg (1) · 50 mg PO BID; titrate to 100-200 mg BID; pill-in-pocket 200-300 mg PO single dose for AF conversion (1)

None (1) · 25 mg, 50 mg, 100 mg tablets; oral concentrate 20 mg/mL (1) · 50, 100, 150 mg tablets (1)

None (1) · 200 mg/d (1) · 400 mg/d (1)

AF conversion within hours of single PO dose (1) · Anxiolysis classically 3-4 weeks, continuing improvement to 8-12 weeks (1) · Mood: 2–4 weeks. Pain: often within 1–2 weeks. (1)

12 hours (1) · Chronic daily dosing (1) · Long (1)

~12 hours (1) · ~14 hours (adults); longer in elderly and renal impairment'"`UNIQ--ref-0000113F-QINU`"' (1) · ~26 h (sertraline; range 13-45 h, longer in females); ~62-104 h (N-desmethylsertraline, weakly active) (1)

Absolute bioavailability not precisely characterized; food modestly increases exposure (1) · ~50% (highly variable) (1) · ~90% (oral)'"`UNIQ--ref-00001140-QINU`"' (1)

Category C (1) · Category C'"`UNIQ--ref-0000008F-QINU`"' (1) · Use in fetal SVT (transplacental antiarrhythmic therapy) is established; otherwise weigh against alternatives.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> (1)

Rx-only (1) · Rx-only in US (1) · [[USLegal:Prescription only|Rx-only]] in US. '''Contraindicated in structural heart disease''' — CAST trial (1989) showed increased mortality from class IC agents in patients with prior MI; modern use is limited to structurally normal hearts'"`UNIQ--ref-00001141-QINU`"' (1)

Showing below up to 3 results in range #1 to #3.

D

Duloxetine

F

Flecainide

S

Sertraline

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