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Medicines (732)

Medicines > classes

: Antidepressant

or [[:Category:Cardiovascular_agents|Cardiovascular agent]]

& routes: Oral

Use the filters below to narrow your results.

Amiodarone (1) · Duloxetine (1) · Sertraline (1)

Cordarone, Pacerone, Nexterone (IV) (1) · Cymbalta, Drizalma Sprinkle, Irenka, Yentreve (1) · Zoloft (1)

None (1) · Serotonin–norepinephrine reuptake inhibition (balanced) (1) · TrkB/BDNF'"`UNIQ--ref-00000084-QINU`"' '"`UNIQ--vote-00000085-QINU`"' (1)

None (1) · Depression, anxiety, neuropathic pain, fibromyalgia, chronic musculoskeletal pain (1) · '"`UNIQ--vote-00000CB0-QINU`"', '"`UNIQ--vote-00000CB1-QINU`"', '"`UNIQ--vote-00000CB2-QINU`"' (1)

None (1) · 25 mg (1) · Oral load 800-1600 mg/d in divided doses for 1-3 weeks, then 600-800 mg/d for 1 month, then 200-400 mg/d maintenance; IV 150 mg over 10 min then 1 mg/min for 6 hours then 0.5 mg/min (1)

None (1) · 100, 200, 400 mg tablets; 50 mg/mL IV (with polysorbate 80 in older formulations causing hypotension); 1.5 mg/mL Nexterone IV (PVC-free, lower hypotension risk) (1) · 25 mg, 50 mg, 100 mg tablets; oral concentrate 20 mg/mL (1)

None (1) · 200 mg/d (1) · Oral maintenance 400 mg/d typical; higher in refractory cases (1)

Anxiolysis classically 3-4 weeks, continuing improvement to 8-12 weeks (1) · IV: minutes; oral: weeks to load (1) · Mood: 2–4 weeks. Pain: often within 1–2 weeks. (1)

Chronic daily dosing (1) · Long (1) · Weeks after discontinuation (extremely long half-life) (1)

~12 hours (1) · ~26 h (sertraline; range 13-45 h, longer in females); ~62-104 h (N-desmethylsertraline, weakly active) (1) · ~58 days (parent); ~61 days (desethylamiodarone, active metabolite)'"`UNIQ--ref-00000CB3-QINU`"' (1)

Absolute bioavailability not precisely characterized; food modestly increases exposure (1) · ~50% (highly variable) (1) · ~50% (oral; highly variable)'"`UNIQ--ref-00000CB4-QINU`"' (1)

Category C (1) · Category C'"`UNIQ--ref-0000008F-QINU`"' (1) · Generally avoided; fetal goiter/hypothyroidism risk (iodine load). Used only for life-threatening arrhythmia.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> (1)

Rx-only (1) · Rx-only in US (1) · [[USLegal:Prescription only|Rx-only]] in US. Carries '''Boxed Warnings''' for pulmonary toxicity (interstitial pneumonitis, fibrosis), hepatotoxicity, and proarrhythmia'"`UNIQ--ref-00000CB5-QINU`"' (1)

Showing below up to 3 results in range #1 to #3.

A

Amiodarone

D

Duloxetine

S

Sertraline

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