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Drilldown: Medicines

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Medicines > classes : Antidepressant or [[:Category:SV2A ligands|Synaptic vesicle protein 2A (SV2A) ligand]] & duration: Long

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generic:
Sertraline (1)
brand:
Zoloft (1)
classes: (Click arrow to add another value)
mechanism:
TrkB/BDNF'"`UNIQ--ref-00000084-QINU`"' '"`UNIQ--vote-00000085-QINU`"' (1)
uses:
None (1)
starting dose:
25 mg (1)
preparations:
25 mg, 50 mg, 100 mg tablets; oral concentrate 20 mg/mL (1)
fda max:
200 mg/d (1)
routes:
Oral (1)
onset:
Anxiolysis classically 3-4 weeks, continuing improvement to 8-12 weeks (1)
duration: (Click arrow to add another value)
halflife:
~26 h (sertraline; range 13-45 h, longer in females); ~62-104 h (N-desmethylsertraline, weakly active) (1)
bioavailability:
Absolute bioavailability not precisely characterized; food modestly increases exposure (1)
pregnancy:
Category C'"`UNIQ--ref-0000008F-QINU`"' (1)
legal:
Rx-only in US (1)

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