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Medicines (732)

Medicines > classes

: Antidepressant

or [[:Category:Vitamin_D_analogs|Vitamin D analog]]

& routes: Oral

Use the filters below to narrow your results.

Cholecalciferol (vitamin D3) (1) · Duloxetine (1) · Ergocalciferol (vitamin D2) (1) · Sertraline (1)

Cymbalta, Drizalma Sprinkle, Irenka, Yentreve (1) · Drisdol, Calcidol; also many OTC preparations (1) · Many OTC; Rx 50,000 IU also available (1) · Zoloft (1)

Serotonin–norepinephrine reuptake inhibition (balanced) (1) · TrkB/BDNF'"`UNIQ--ref-00000084-QINU`"' '"`UNIQ--vote-00000085-QINU`"' (1) · '"`UNIQ--vote-0000032A-QINU`"' D3 (cholecalciferol) is more potent at raising serum 25(OH)D per dose; D2 remains widely prescribed in the US Rx 50,000 IU formulation'"`UNIQ--ref-0000032B-QINU`"'. (1) · '"`UNIQ--vote-0000042C-QINU`"' D3 is more potent than D2 at raising and sustaining serum 25(OH)D per dose, and is the more common OTC formulation; D2 remains the dominant Rx 50,000 IU formulation in the US for historical reasons. (1)

None (1) · Depression, anxiety, neuropathic pain, fibromyalgia, chronic musculoskeletal pain (1) · '"`UNIQ--vote-0000032C-QINU`"', '"`UNIQ--vote-0000032D-QINU`"', '"`UNIQ--vote-0000032E-QINU`"', '"`UNIQ--vote-0000032F-QINU`"' (1) · '"`UNIQ--vote-0000042D-QINU`"', '"`UNIQ--vote-0000042E-QINU`"', '"`UNIQ--vote-0000042F-QINU`"', '"`UNIQ--vote-00000430-QINU`"' (1)

None (1) · 25 mg (1) · Deficiency: 50,000 IU PO weekly for 8-12 weeks, then maintenance 800-2,000 IU/day; maintenance OTC dosing typically 800-2,000 IU/d (1) · Maintenance 800-2,000 IU PO daily; deficiency replacement 50,000 IU PO weekly for 8-12 weeks then maintenance, or equivalent daily dosing 5,000-10,000 IU/d (1)

None (1) · 25 mg, 50 mg, 100 mg tablets; oral concentrate 20 mg/mL (1) · 50,000 IU capsules (Rx); 8,000 IU/mL oral solution (Rx); 400-5,000 IU OTC tablets and softgels (1) · OTC 400, 1,000, 2,000, 5,000 IU softgels and tablets; Rx 50,000 IU capsules; liquid drops 400-2,000 IU/drop (1)

None (1) · 200 mg/d (1) · No strict; Institute of Medicine UL 4,000 IU/d in adults for chronic use (1) · Not strictly fixed; long-term Upper Limit ~4,000 IU/d in adults (Institute of Medicine) (1)

Anxiolysis classically 3-4 weeks, continuing improvement to 8-12 weeks (1) · Days to weeks to raise 25(OH)D; clinical effect on bone over months (1) · Mood: 2–4 weeks. Pain: often within 1–2 weeks. (1) · Weeks to raise 25(OH)D into reference range (1)

Chronic daily dosing (1) · Long (1) · Long; fat-soluble storage in adipose (1) · Long; fat-soluble, stored in adipose (1)

~12 hours (1) · ~24 hours (parent); ~15 days (25(OH)D); 25(OH)D stores persist for months'"`UNIQ--ref-00000330-QINU`"' (1) · ~24 hours (parent); ~15 days (25(OH)D); tissue stores months (1) · ~26 h (sertraline; range 13-45 h, longer in females); ~62-104 h (N-desmethylsertraline, weakly active) (1)

Absolute bioavailability not precisely characterized; food modestly increases exposure (1) · ~50% (highly variable) (1) · ~75% (oral; absorption improved with fat-containing meal) (1) · ~75% (oral; fat-soluble, absorption requires intact biliary/lipid digestion)'"`UNIQ--ref-00000331-QINU`"' (1)

Category C (1) · Category C'"`UNIQ--ref-0000008F-QINU`"' (1) · Safe at replacement doses; deficiency is itself a risk in pregnancy and lactation.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> (2)

OTC (low-dose) and [[USLegal:Prescription only|Rx-only]] (50,000 IU and concentrated solutions) in US (1) · OTC (most) and [[USLegal:Prescription only|Rx-only]] (50,000 IU) in US (1) · Rx-only (1) · Rx-only in US (1)

Showing below up to 4 results in range #1 to #4.

C

Cholecalciferol

D

Duloxetine

E

Ergocalciferol

S

Sertraline

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