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Drilldown: Medicines

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Medicines > classes : Antidepressant or Antiparkinsonian or Antipsychotic

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generic:
brand:
None (2)
classes: (Click arrow to add another value)
mechanism:
Phenothiazine D2 antagonist (5) · Irreversible non-selective MAO inhibitor (3) · Selective norepinephrine reuptake inhibitor (3) · Serotonin and norepinephrine reuptake inhibitor (3) · Irreversible selective MAO-B inhibitor (2) · Serotonin–norepinephrine reuptake inhibitor (2)
uses:
None (51) · Depression, anxiety, neuropathic pain, fibromyalgia, chronic musculoskeletal pain (1)
starting dose:
None (51) · 25 mg (1)
preparations:
None (51) · 25 mg, 50 mg, 100 mg tablets; oral concentrate 20 mg/mL (1)
fda max:
None (51) · 200 mg/d (1)
routes:
None (50) · Oral (2)
onset:
None (50) · Anxiolysis classically 3-4 weeks, continuing improvement to 8-12 weeks (1) · Mood: 2–4 weeks. Pain: often within 1–2 weeks. (1)
duration:
None (50) · Chronic daily dosing (1) · Long (1)
halflife:
None (50) · ~12 hours (1) · ~26 h (sertraline; range 13-45 h, longer in females); ~62-104 h (N-desmethylsertraline, weakly active) (1)
bioavailability:
None (50) · Absolute bioavailability not precisely characterized; food modestly increases exposure (1) · ~50% (highly variable) (1)
pregnancy:
None (50) · Category C (1) · Category C'"`UNIQ--ref-0000008F-QINU`"' (1)
legal:
None (50) · Rx-only (1) · Rx-only in US (1)

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