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Drilldown: Medicines

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Medicines > classes : Antidepressant or Botanical or Neuroleptic

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generic:
brand:
None (24) · Anafranil (1) · Aurorix (1) · Clozaril (1) · Cymbalta, Drizalma Sprinkle, Irenka, Yentreve (1) · Edronax (1) · Fanapt (1) · Fetzima (1) · Geodon (1) · Inapsine (1) · Invega (1) · Latuda (1) · Loxitane (1) · Ludiomil (1) · Marplan (1) · Mellaril (1) · Moban (1) · Nardil (1) · Navane (1) · Norpramin (1) · Orap (1) · Parnate (1) · Prolixin (1) · Saphris (1) · Savella (1) · Serzone (1) · Stablon (1) · Stelazine (1) · Surmontil (1) · Thorazine (1) · Tofranil (1) · Trilafon (1) · Valdoxan (1) · Vivactil (1) · Zoloft (1)
classes: (Click arrow to add another value)
mechanism:
Phenothiazine D2 antagonist (4) · Irreversible non-selective MAO inhibitor (3) · Selective norepinephrine reuptake inhibitor (3) · Serotonin and norepinephrine reuptake inhibitor (3) · Contains LSA (2) · Contains mescaline (2) · Serotonin–norepinephrine reuptake inhibitor (2)
uses:
None (57) · Depression, anxiety, neuropathic pain, fibromyalgia, chronic musculoskeletal pain (1)
starting dose:
None (57) · 25 mg (1)
preparations:
None (57) · 25 mg, 50 mg, 100 mg tablets; oral concentrate 20 mg/mL (1)
fda max:
None (57) · 200 mg/d (1)
routes:
None (56) · Oral (2)
onset:
None (56) · Anxiolysis classically 3-4 weeks, continuing improvement to 8-12 weeks (1) · Mood: 2–4 weeks. Pain: often within 1–2 weeks. (1)
duration:
None (56) · Chronic daily dosing (1) · Long (1)
halflife:
None (56) · ~12 hours (1) · ~26 h (sertraline; range 13-45 h, longer in females); ~62-104 h (N-desmethylsertraline, weakly active) (1)
bioavailability:
None (56) · Absolute bioavailability not precisely characterized; food modestly increases exposure (1) · ~50% (highly variable) (1)
pregnancy:
None (56) · Category C (1) · Category C'"`UNIQ--ref-0000008F-QINU`"' (1)
legal:
None (56) · Rx-only (1) · Rx-only in US (1)

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