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Medicines (732)

Medicines > classes

: Antidepressant

or Multimodal serotonergic; HSDD treatment

& routes: Oral

Use the filters below to narrow your results.

Duloxetine (1) · Flibanserin (1) · Sertraline (1)

Addyi (1) · Cymbalta, Drizalma Sprinkle, Irenka, Yentreve (1) · Zoloft (1)

5-HT1A agonist, 5-HT2A antagonist, with weaker activity at D4 and other receptors. Net effect involves enhanced prefrontal dopaminergic/noradrenergic tone with decreased serotonergic inhibition of sexual desire. (1) · Serotonin–norepinephrine reuptake inhibition (balanced) (1) · TrkB/BDNF'"`UNIQ--ref-00000084-QINU`"' '"`UNIQ--vote-00000085-QINU`"' (1)

None (1) · Depression, anxiety, neuropathic pain, fibromyalgia, chronic musculoskeletal pain (1) · '"`UNIQ--vote-000002C1-QINU`"' (1)

None (1) · 100 mg at bedtime daily (1) · 25 mg (1)

None (1) · 100 mg tabs (1) · 25 mg, 50 mg, 100 mg tablets; oral concentrate 20 mg/mL (1)

None (1) · 100 mg/d (1) · 200 mg/d (1)

Anxiolysis classically 3-4 weeks, continuing improvement to 8-12 weeks (1) · Effects accumulate over weeks; assess at 8 weeks (1) · Mood: 2–4 weeks. Pain: often within 1–2 weeks. (1)

Chronic daily dosing (1) · Continuous daily dosing (1) · Long (1)

~11 h (1) · ~12 hours (1) · ~26 h (sertraline; range 13-45 h, longer in females); ~62-104 h (N-desmethylsertraline, weakly active) (1)

Absolute bioavailability not precisely characterized; food modestly increases exposure (1) · ~33% (1) · ~50% (highly variable) (1)

Category C (1) · Category C'"`UNIQ--ref-0000008F-QINU`"' (1) · Not indicated; pregnancy effects unknown (1)

Rx-only (1) · Rx-only in US (1) · Rx-only in US (REMS program) (1)

Showing below up to 3 results in range #1 to #3.

D

Duloxetine

F

Flibanserin

S

Sertraline

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