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Medicines (732)

Medicines > classes

: Antidepressant

or Non-selective

& routes: Oral

Use the filters below to narrow your results.

Duloxetine (1) · Propranolol (1) · Sertraline (1)

Cymbalta, Drizalma Sprinkle, Irenka, Yentreve (1) · Inderal (1) · Zoloft (1)

Non-selective competitive antagonist at β1 and β2 adrenergic receptors. Lipophilic; significant blood–brain barrier penetration, accounting for its CNS effects. (1) · Serotonin–norepinephrine reuptake inhibition (balanced) (1) · TrkB/BDNF'"`UNIQ--ref-00000084-QINU`"' '"`UNIQ--vote-00000085-QINU`"' (1)

None (1) · Depression, anxiety, neuropathic pain, fibromyalgia, chronic musculoskeletal pain (1) · '"`UNIQ--vote-000005E7-QINU`"', '"`UNIQ--vote-000005E8-QINU`"', '"`UNIQ--vote-000005E9-QINU`"', '"`UNIQ--vote-000005EA-QINU`"', '"`UNIQ--vote-000005EB-QINU`"' (1)

None (1) · 10–40 mg (situational anxiety); 40 mg BID (HTN) (1) · 25 mg (1)

None (1) · 10, 20, 40, 60, 80 mg tabs; 60/80/120/160 mg ER caps; 1 mg/mL IV (1) · 25 mg, 50 mg, 100 mg tablets; oral concentrate 20 mg/mL (1)

None (1) · 200 mg/d (1) · 640 mg/d (HTN); 240 mg/d (migraine) (1)

1–2 h (PO), immediate (IV) (1) · Anxiolysis classically 3-4 weeks, continuing improvement to 8-12 weeks (1) · Mood: 2–4 weeks. Pain: often within 1–2 weeks. (1)

6–12 h (IR); 24 h (ER) (1) · Chronic daily dosing (1) · Long (1)

3–6 h (1) · ~12 hours (1) · ~26 h (sertraline; range 13-45 h, longer in females); ~62-104 h (N-desmethylsertraline, weakly active) (1)

Absolute bioavailability not precisely characterized; food modestly increases exposure (1) · ~25% (extensive hepatic first-pass) (1) · ~50% (highly variable) (1)

Category C (2) · Category C'"`UNIQ--ref-0000008F-QINU`"' (1)

Rx-only (1) · Rx-only in US (2)

Showing below up to 3 results in range #1 to #3.

D

Duloxetine

P

Propranolol

S

Sertraline

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