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Medicines (732)

Medicines > classes

: Antidepressant

or Xanthine

& routes: Oral

Use the filters below to narrow your results.

Coffee (1) · Duloxetine (1) · Sertraline (1)

''Coffea arabica'', ''Coffea canephora'' (robusta) (1) · Cymbalta, Drizalma Sprinkle, Irenka, Yentreve (1) · Zoloft (1)

Caffeine is a non-selective adenosine A1/A2A receptor antagonist; also weak PDE inhibition. Beans contain theobromine (3,7-DMX) and theophylline (1,3-DMX) in smaller amounts. (1) · Serotonin–norepinephrine reuptake inhibition (balanced) (1) · TrkB/BDNF'"`UNIQ--ref-00000084-QINU`"' '"`UNIQ--vote-00000085-QINU`"' (1)

None (1) · Depression, anxiety, neuropathic pain, fibromyalgia, chronic musculoskeletal pain (1) · '"`UNIQ--vote-000000CF-QINU`"', '"`UNIQ--vote-000000D0-QINU`"', '"`UNIQ--vote-000000D1-QINU`"' (1)

None (1) · 25 mg (1) · One cup (~80–145 mg caffeine for brewed; 60–100 mg for instant) (1)

None (1) · 25 mg, 50 mg, 100 mg tablets; oral concentrate 20 mg/mL (1) · Roasted beans, ground; brewed (drip, French press, espresso, cold brew, percolated) (1)

None (2) · 200 mg/d (1)

Anxiolysis classically 3-4 weeks, continuing improvement to 8-12 weeks (1) · Mood: 2–4 weeks. Pain: often within 1–2 weeks. (1) · ~15–30 min (1)

3–5 h (subjective) (1) · Chronic daily dosing (1) · Long (1)

~12 hours (1) · ~26 h (sertraline; range 13-45 h, longer in females); ~62-104 h (N-desmethylsertraline, weakly active) (1) · ~5 h (caffeine) (1)

Absolute bioavailability not precisely characterized; food modestly increases exposure (1) · ~50% (highly variable) (1) · ~99% (caffeine) (1)

Category C (1) · Category C'"`UNIQ--ref-0000008F-QINU`"' (1) · Limit to <200 mg/d (~2 cups brewed) (1)

Rx-only (1) · Rx-only in US (1) · Unrestricted (food) (1)

Showing below up to 3 results in range #1 to #3.

C

Coffee

D

Duloxetine

S

Sertraline

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