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Medicines > classes : Antiparkinsonian or Classic Psychedelic or [[:Category:Progestins|Progestin (synthetic progestogen)]]

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generic:
brand:
None (70) · Akineton (1) · Apokyn (1) · Artane (1) · Aygestin (5 mg, Rx); Camila, Errin, Heather, Jolivette, Nor-QD, Ortho Micronor, Sharobel (0.35 mg POPs); component of many COCs (1) · Azilect (1) · Cogentin (1) · Comtan (1) · Delysid (historical, Sandoz, withdrawn 1965) (1) · Dostinex (1) · Eldepryl (1) · Neupro (1) · Ongentys (1) · Parlodel (1) · Sinemet (1) · Symmetrel (1) · Tasmar (1) · Xadago (1)
classes: (Click arrow to add another value)
mechanism:
5-HT2A agonist (26) · Potent 5-HT2A agonist (5) · LSD analogue; 5-HT2A agonist (4) · Prodrug of LSD; 5-HT2A agonist (4) · Contains LSA (2) · Contains mescaline (2) · Irreversible selective MAO-B inhibitor (2)
uses:
None (86) · '"`UNIQ--vote-000013F0-QINU`"', '"`UNIQ--vote-000013F1-QINU`"', '"`UNIQ--vote-000013F2-QINU`"', '"`UNIQ--vote-000013F3-QINU`"', '"`UNIQ--vote-000013F4-QINU`"' (1)
starting dose:
None (86) · POP: 0.35 mg PO daily continuously (no placebo week); high-dose 5 mg Aygestin for amenorrhea/endometriosis 5-10 mg/d (1)
preparations:
None (86) · 0.35 mg POP tablets; 5 mg tablets (Aygestin); component of COCs and combination HRT (1)
fda max:
None (86) · Indication-specific (1)
routes:
None (85) · Oral (2)
onset:
None (85) · 30–60 minutes (1) · Contraception within 48 hours of starting (POP); endometrial effects days (1)
duration:
None (85) · 8–12 hours (1) · ~24 hours per dose (strict timing required for POP — within 3-hour window each day) (1)
halflife:
None (85) · 3–5 hours (1) · ~8 hours'"`UNIQ--ref-000013F5-QINU`"' (1)
bioavailability:
None (85) · 70–90% (oral) (1) · ~65% (oral)'"`UNIQ--ref-000013F6-QINU`"' (1)
pregnancy:
None (85) · Contraindicated in known pregnancy (Aygestin); the 0.35 mg POP is not teratogenic and does not need to be discontinued before conception planning.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1) · Not established (1)
legal:
None (85) · Schedule I (United States) (1) · [[USLegal:Prescription only|Rx-only]] in US (note: norgestrel 0.075 mg POP is now OTC as Opill since 2023, but norethindrone POP remains Rx) (1)

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