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Medicines > classes : Antiparkinsonian or Classic Psychedelic or [[:Category:Progestogens|Progestogen]]

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generic:
brand:
None (70) · Akineton (1) · Apokyn (1) · Artane (1) · Azilect (1) · Cogentin (1) · Comtan (1) · Delysid (historical, Sandoz, withdrawn 1965) (1) · Dostinex (1) · Eldepryl (1) · Neupro (1) · Ongentys (1) · Parlodel (1) · Prometrium (oral), Endometrin (vaginal), Crinone (vaginal gel), Prochieve (1) · Sinemet (1) · Symmetrel (1) · Tasmar (1) · Xadago (1)
classes: (Click arrow to add another value)
mechanism:
5-HT2A agonist (26) · Potent 5-HT2A agonist (5) · LSD analogue; 5-HT2A agonist (4) · Prodrug of LSD; 5-HT2A agonist (4) · Contains LSA (2) · Contains mescaline (2) · Irreversible selective MAO-B inhibitor (2)
uses:
None (86) · '"`UNIQ--vote-00000722-QINU`"', '"`UNIQ--vote-00000723-QINU`"', '"`UNIQ--vote-00000724-QINU`"', '"`UNIQ--vote-00000725-QINU`"' (1)
starting dose:
None (86) · HRT cyclic: 200 mg PO HS days 1-12 of each month; continuous: 100 mg PO daily; ART luteal support 100 mg vaginal TID or 90 mg gel daily (1)
preparations:
None (86) · Oral 100, 200 mg capsules (peanut oil; check allergy); 100 mg vaginal insert (Endometrin); 4%, 8% vaginal gel (Crinone); IM 50 mg/mL (1)
fda max:
None (86) · Indication-dependent; 200-400 mg/d oral typical (1)
routes:
None (85) · intramuscular (1) · Oral (2) · vaginal (1)
onset:
None (85) · 30–60 minutes (1) · Sedation/dizziness within hours of oral dose; endometrial effects over days (1)
duration:
None (85) · 8–12 hours (1) · Oral: 8-12 hours; vaginal: 24+ hours; IM: days (1)
halflife:
None (85) · 3–5 hours (1) · ~5-20 hours (oral micronized; highly variable)'"`UNIQ--ref-00000726-QINU`"' (1)
bioavailability:
None (85) · 70–90% (oral) (1) · Oral: very low (extensive first-pass); micronization improves uptake somewhat. Vaginal: high local effect with lower systemic levels (first-uterine-pass concentration)'"`UNIQ--ref-00000727-QINU`"' (1)
pregnancy:
None (86) · Not established (1)
legal:
None (85) · Schedule I (United States) (1) · [[USLegal:Prescription only|Rx-only]] in US (1)

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