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Medicines > classes : Benzodiazepine or [[:Category:Penicillins|Penicillin]] & routes: Oral

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generic:
Alprazolam (1) · Amoxicillin (1)
brand:
Amoxil, Trimox, Moxatag; mostly prescribed generically (1) · Xanax (1)
classes: (Click arrow to add another value)
mechanism:
GABA-A positive allosteric modulator'"`UNIQ--ref-00000067-QINU`"' '"`UNIQ--vote-00000068-QINU`"' (1) · '"`UNIQ--vote-00000199-QINU`"' Extends ampicillin's spectrum with better oral bioavailability. Susceptible to β-lactamases; clavulanate co-administration restores activity against many resistant organisms'"`UNIQ--ref-0000019A-QINU`"'. (1)
uses:
'"`UNIQ--vote-00000069-QINU`"', '"`UNIQ--vote-0000006A-QINU`"', '"`UNIQ--vote-0000006B-QINU`"' (1) · '"`UNIQ--vote-0000019B-QINU`"', '"`UNIQ--vote-0000019C-QINU`"', '"`UNIQ--vote-0000019D-QINU`"', '"`UNIQ--vote-0000019E-QINU`"', '"`UNIQ--vote-0000019F-QINU`"', '"`UNIQ--vote-000001A0-QINU`"' (1)
starting dose:
0.25 mg (1) · 500 mg PO TID or 875 mg PO BID for most indications; 80-90 mg/kg/d divided BID in pediatric otitis media (1)
preparations:
0.25 mg, 0.5 mg, 1 mg, 2 mg tablets (immediate-release and orally disintegrating); 0.5 mg, 1 mg, 2 mg, 3 mg extended-release tablets; 1 mg/mL oral concentrate (1) · 250 mg, 500 mg capsules; 500 mg, 875 mg tablets; 125, 200, 250, 400 mg/5 mL oral suspension; 775 mg ER; 50 mg/mL drops (1)
fda max:
10 mg/d (1) · 3 g/d typical; higher in severe infections under specialist guidance (1)
routes: (Click arrow to add another value)
onset:
30-60 min (immediate-release); 1-2 h (extended-release) (1) · Peak plasma at 1-2 hours; clinical effect within 24-72 hours (1)
duration:
6 h (immediate-release); ~11 h (extended-release) (1) · ~8 hours per dose (1)
halflife:
1-1.3 hours'"`UNIQ--ref-000001A1-QINU`"' (1) · 11-13 h (immediate-release); 11-16 h (extended-release) (1)
bioavailability:
75-90% (oral; minimally affected by food)'"`UNIQ--ref-000001A2-QINU`"' (1) · 80-90% oral (1)
pregnancy:
Category D'"`UNIQ--ref-0000006C-QINU`"' (1) · Generally considered safe; widely used in pregnancy and lactation.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
Schedule IV (US) (1) · [[USLegal:Prescription only|Rx-only]] in US (1)

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