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Medicines > classes : Benzodiazepine or Classic Psychedelic or [[:Category:Dissociatives|Dissociative]]

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generic:
brand:
None (78) · Dalmane (1) · Delysid (historical, Sandoz, withdrawn 1965) (1) · Doral (1) · Halcion (1) · Lexotan (1) · Librium (1) · Mogadon (1) · Onfi (1) · ProSom (1) · Restoril (1) · Rohypnol (1) · Serax (1) · Sernyl (human, withdrawn 1965); Sernylan (veterinary, withdrawn 1978) (1) · Tranxene (1) · Versed (1) · Xanax (1)
classes: (Click arrow to add another value)
mechanism:
5-HT2A agonist (26) · GABAA positive allosteric modulator (18) · Potent 5-HT2A agonist (5) · LSD analogue; 5-HT2A agonist (4) · Prodrug of LSD; 5-HT2A agonist (4) · Contains LSA (2) · Contains mescaline (2)
uses:
None (92) · '"`UNIQ--vote-00000063-QINU`"', '"`UNIQ--vote-00000064-QINU`"' (1) · '"`UNIQ--vote-00000069-QINU`"', '"`UNIQ--vote-0000006A-QINU`"', '"`UNIQ--vote-0000006B-QINU`"' (1)
starting dose:
None (92) · 0.25 mg (1) · No current medical indication. Historical anesthetic dose 0.25 mg/kg IV (Sernyl). (1)
preparations:
None (92) · 0.25 mg, 0.5 mg, 1 mg, 2 mg tablets (immediate-release and orally disintegrating); 0.5 mg, 1 mg, 2 mg, 3 mg extended-release tablets; 1 mg/mL oral concentrate (1) · Historical: Sernyl 25 mg tablets, 10 mg/mL injection (human); Sernylan 100 mg/mL injection (veterinary). Illicit: white crystalline powder, oily liquid, "dipped" cigarettes ("wet"), tablets. (1)
fda max:
None (92) · 10 mg/d (1) · N/A (no current medical indication) (1)
routes:
None (91) · IM (1) · insufflated (1) · IV (1) · Oral (3) · smoked (1)
onset:
None (91) · 30-60 min (immediate-release); 1-2 h (extended-release) (1) · 30–60 minutes (1) · Smoked 2-5 min; insufflated 5-15 min; oral 30-60 min; IV / IM ~5-15 min (1)
duration:
None (91) · 4-8 hours typical; longer at high doses; residual cognitive and perceptual effects up to 48 hours (1) · 6 h (immediate-release); ~11 h (extended-release) (1) · 8–12 hours (1)
halflife:
None (91) · 11-13 h (immediate-release); 11-16 h (extended-release) (1) · 3–5 hours (1) · Highly variable, 7-46 hours (mean ~21 h); lipophilic deposition in fat with delayed re-release contributes to wide range'"`UNIQ--ref-00000065-QINU`"' (1)
bioavailability:
None (91) · 70–90% (oral) (1) · 80-90% oral (1) · ~72% oral; ~85% smoked'"`UNIQ--ref-00000066-QINU`"' (1)
pregnancy:
None (92) · Category D'"`UNIQ--ref-0000006C-QINU`"' (1) · Not established (1)
legal:
None (91) · Schedule I (United States) (1) · Schedule IV (US) (1) · [[USLegal:DEA Schedule II|Schedule II]] controlled substance in US (rescheduled from Schedule III in 1978). No accepted medical use. UN Convention on Psychotropic Substances Schedule II internationally.'"`UNIQ--ref-00000067-QINU`"' (1)

Showing below up to 94 results in range #1 to #94.

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