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Medicines > classes : Benzodiazepine or Classic Psychedelic or GABAB Agonist; Endogenous GHB receptor agonist

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generic:
brand:
None (78) · Dalmane (1) · Delysid (historical, Sandoz, withdrawn 1965) (1) · Doral (1) · Halcion (1) · Lexotan (1) · Librium (1) · Mogadon (1) · Onfi (1) · ProSom (1) · Restoril (1) · Rohypnol (1) · Serax (1) · Tranxene (1) · Versed (1) · Xanax (1) · Xyrem; Xywav (lower-sodium formulation with Ca/Mg/K salts) (1)
classes: (Click arrow to add another value)
mechanism:
5-HT2A agonist (26) · GABAA positive allosteric modulator (18) · Potent 5-HT2A agonist (5) · LSD analogue; 5-HT2A agonist (4) · Prodrug of LSD; 5-HT2A agonist (4) · Contains LSA (2) · Contains mescaline (2)
uses:
None (92) · '"`UNIQ--vote-00000069-QINU`"', '"`UNIQ--vote-0000006A-QINU`"', '"`UNIQ--vote-0000006B-QINU`"' (1) · '"`UNIQ--vote-00000717-QINU`"', '"`UNIQ--vote-00000718-QINU`"', '"`UNIQ--vote-00000719-QINU`"' (1)
starting dose:
None (92) · 0.25 mg (1) · 2.25 g at bedtime + 2.25 g 2.5–4 h later; titrate weekly to 6–9 g/night total (1)
preparations:
None (92) · 0.25 mg, 0.5 mg, 1 mg, 2 mg tablets (immediate-release and orally disintegrating); 0.5 mg, 1 mg, 2 mg, 3 mg extended-release tablets; 1 mg/mL oral concentrate (1) · 0.5 g/mL oral solution (1)
fda max:
None (92) · 10 mg/d (1) · 9 g/night (1)
routes:
None (91) · Oral (2) · Oral (must be taken in bed; effects within minutes) (1)
onset:
None (91) · 15–30 min (fasting) (1) · 30-60 min (immediate-release); 1-2 h (extended-release) (1) · 30–60 minutes (1)
duration:
None (91) · 6 h (immediate-release); ~11 h (extended-release) (1) · 8–12 hours (1) · ~3 h per dose (twice-nightly schedule required) (1)
halflife:
None (91) · 11-13 h (immediate-release); 11-16 h (extended-release) (1) · 30–60 min (1) · 3–5 hours (1)
bioavailability:
None (91) · 70–90% (oral) (1) · 80-90% oral (1) · ~25% (high first-pass) (1)
pregnancy:
None (91) · Category C (1) · Category D'"`UNIQ--ref-0000006C-QINU`"' (1) · Not established (1)
legal:
None (91) · Schedule I (United States) (1) · Schedule III; REMS-restricted (Schedule I if outside the pharmaceutical channel, same molecule as illicit GHB) (1) · Schedule IV (US) (1)

Showing below up to 94 results in range #1 to #94.

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