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Medicines > classes : Benzodiazepine or Empathogenica & routes: Oral

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generic:
Alprazolam (1) · Nutmeg (1)
brand:
''Myristica fragrans''. Mace (the fruit aril) (1) · Xanax (1)
classes: (Click arrow to add another value)
mechanism:
Active oils are myristicin, elemicin, and safrole, phenethylamine precursors that may be aminated in vivo to MMDA, TMA, and MDA respectively (Shulgin's 'essential amphetamines' hypothesis). (1) · GABA-A positive allosteric modulator'"`UNIQ--ref-00000067-QINU`"' '"`UNIQ--vote-00000068-QINU`"' (1)
uses:
'"`UNIQ--vote-00000006-QINU`"' (1) · '"`UNIQ--vote-00000069-QINU`"', '"`UNIQ--vote-0000006A-QINU`"', '"`UNIQ--vote-0000006B-QINU`"' (1)
starting dose:
0.25 mg (1) · 0.5–1 oz (10–30 g) ground for psychoactive effect; far smaller for culinary use (1)
preparations:
0.25 mg, 0.5 mg, 1 mg, 2 mg tablets (immediate-release and orally disintegrating); 0.5 mg, 1 mg, 2 mg, 3 mg extended-release tablets; 1 mg/mL oral concentrate (1) · Ground dried seed (nutmeg) or fruit aril (mace); occasionally infused (1)
fda max:
None (1) · 10 mg/d (1)
routes: (Click arrow to add another value)
onset:
30-60 min (immediate-release); 1-2 h (extended-release) (1) · Slow, 2–6 h (1)
duration:
12–24 h or longer (1) · 6 h (immediate-release); ~11 h (extended-release) (1)
halflife:
None (1) · 11-13 h (immediate-release); 11-16 h (extended-release) (1)
bioavailability:
None (1) · 80-90% oral (1)
pregnancy:
None (1) · Category D'"`UNIQ--ref-0000006C-QINU`"' (1)
legal:
None (1) · Schedule IV (US) (1)

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