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Drilldown: Medicines

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Medicines > classes : Botanical or Classic Psychedelic or [[:Category:Psychostimulants|Psychostimulant]] (atypical)

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generic:
brand:
None (85) · Delysid (historical, Sandoz, withdrawn 1965) (1) · Provigil (Teva/Cephalon); Alertec (Canada); Modavigil (Australia) (1)
classes: (Click arrow to add another value)
mechanism:
5-HT2A agonist (26) · Potent 5-HT2A agonist (5) · LSD analogue; 5-HT2A agonist (4) · Prodrug of LSD; 5-HT2A agonist (4) · Contains LSA (2) · Contains mescaline (2)
uses:
None (87)
starting dose:
None (87)
preparations:
None (86) · Tablets: 100 mg, 200 mg (scored). [[Armodafinil]] (Nuvigil), the R-enantiomer of modafinil, is available separately as 50 mg, 150 mg, 200 mg, and 250 mg tablets. (1)
fda max:
None (86) · 400 mg/day.'"`UNIQ--ref-0000006C-QINU`"' (1)
routes:
None (85) · Oral (2)
onset:
None (85) · 30–60 minutes (1) · Peak plasma concentration in 2-4 hours after oral administration. Clinically perceptible wakefulness-promoting effects typically begin within 1-2 hours of dosing.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
duration:
None (85) · 8–12 hours (1) · Effective duration approximately 12-15 hours at the 200 mg dose, consistent with the elimination half-life. A single morning dose generally sustains wakefulness throughout the day without substantially disrupting nighttime sleep onset when taken early.'"`UNIQ--ref-0000006D-QINU`"' (1)
halflife:
None (86) · 3–5 hours (1)
bioavailability:
None (85) · 70–90% (oral) (1) · Oral bioavailability is not precisely established in the label but absorption is rapid and essentially complete. Food delays peak plasma concentration by approximately one hour but does not reduce the extent of absorption.'"`UNIQ--ref-0000006F-QINU`"' (1)
pregnancy:
None (86) · Not established (1)
legal:
None (86) · Schedule I (United States) (1)

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