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Drilldown: Medicines

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Medicines > classes : Botanical or Classic Psychedelic or GABAB Agonist; Endogenous GHB receptor agonist

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generic:
brand:
None (85) · Delysid (historical, Sandoz, withdrawn 1965) (1) · Xyrem; Xywav (lower-sodium formulation with Ca/Mg/K salts) (1)
classes: (Click arrow to add another value)
mechanism:
5-HT2A agonist (26) · Potent 5-HT2A agonist (5) · LSD analogue; 5-HT2A agonist (4) · Prodrug of LSD; 5-HT2A agonist (4) · Contains LSA (2) · Contains mescaline (2)
uses:
None (86) · '"`UNIQ--vote-00000717-QINU`"', '"`UNIQ--vote-00000718-QINU`"', '"`UNIQ--vote-00000719-QINU`"' (1)
starting dose:
None (86) · 2.25 g at bedtime + 2.25 g 2.5–4 h later; titrate weekly to 6–9 g/night total (1)
preparations:
None (86) · 0.5 g/mL oral solution (1)
fda max:
None (86) · 9 g/night (1)
routes:
None (85) · Oral (1) · Oral (must be taken in bed; effects within minutes) (1)
onset:
None (85) · 15–30 min (fasting) (1) · 30–60 minutes (1)
duration:
None (85) · 8–12 hours (1) · ~3 h per dose (twice-nightly schedule required) (1)
halflife:
None (85) · 30–60 min (1) · 3–5 hours (1)
bioavailability:
None (85) · 70–90% (oral) (1) · ~25% (high first-pass) (1)
pregnancy:
None (85) · Category C (1) · Not established (1)
legal:
None (85) · Schedule I (United States) (1) · Schedule III; REMS-restricted (Schedule I if outside the pharmaceutical channel, same molecule as illicit GHB) (1)

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