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Drilldown: Medicines

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Medicines > classes : Botanical or Classic Psychedelic or narrow-spectrum)]]

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generic:
brand:
None (85) · Bicillin L-A (benzathine), Bicillin C-R (combination procaine + benzathine), Pfizerpen (potassium IV) (1) · Delysid (historical, Sandoz, withdrawn 1965) (1) · Pen-V, Veetids (mostly generic) (1)
classes: (Click arrow to add another value)
mechanism:
5-HT2A agonist (26) · Potent 5-HT2A agonist (5) · LSD analogue; 5-HT2A agonist (4) · Prodrug of LSD; 5-HT2A agonist (4) · None (2) · Contains LSA (2) · Contains mescaline (2)
uses:
None (86) · '"`UNIQ--vote-00000E71-QINU`"', '"`UNIQ--vote-00000E72-QINU`"', '"`UNIQ--vote-00000E73-QINU`"', '"`UNIQ--vote-00000E74-QINU`"', '"`UNIQ--vote-00000E75-QINU`"' (1) · '"`UNIQ--vote-00001414-QINU`"', '"`UNIQ--vote-00001415-QINU`"', '"`UNIQ--vote-00001416-QINU`"', '"`UNIQ--vote-00001417-QINU`"', '"`UNIQ--vote-00001418-QINU`"' (1)
starting dose:
None (87) · 250-500 mg PO every 6-8 hours (1)
preparations:
None (86) · 250 mg, 500 mg tablets; 125 mg/5 mL, 250 mg/5 mL suspension (1) · Bicillin L-A 600,000; 1.2M; 2.4M U IM; aqueous crystalline (Pfizerpen) 5M, 20M U IV; procaine 600,000 U/mL IM (1)
fda max:
None (86) · 2 g/d typical (1) · Indication-specific (1)
routes:
None (85) · IM (benzathine (1) · IV (aqueous crystalline); '''NEVER IV for benzathine — fatal cardiopulmonary events reported''' (1) · Oral (2) · procaine) (1)
onset:
None (85) · 30–60 minutes (1) · Hours (1) · IV: minutes; IM benzathine: depot levels last weeks (1)
duration:
None (85) · 6-8 hours (1) · 8–12 hours (1) · IM benzathine: 3-4 weeks of detectable levels (1)
halflife:
None (85) · 3–5 hours (1) · Aqueous crystalline ~30 minutes; benzathine effective ~3 weeks via depot release'"`UNIQ--ref-00001419-QINU`"' (1) · ~30-60 minutes'"`UNIQ--ref-00000E76-QINU`"' (1)
bioavailability:
None (85) · 70–90% (oral) (1) · Acid-labile; not effective orally (oral form available outside US as penicillin G salts but penicillin V is preferred for oral use)'"`UNIQ--ref-0000141A-QINU`"' (1) · ~60% (oral; phenoxymethyl modification makes it acid-stable, unlike penicillin G which is destroyed by gastric acid)'"`UNIQ--ref-00000E77-QINU`"' (1)
pregnancy:
None (85) · Generally considered safe; widely used.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1) · Not established (1) · Penicillin G is the only fully effective syphilis treatment in pregnancy; penicillin-allergic pregnant patients require desensitization.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
None (85) · Schedule I (United States) (1) · [[USLegal:Prescription only|Rx-only]] in US (2)

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