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Drilldown: Medicines

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Medicines > classes : Botanical or Classic Psychedelic or super-potent)]]

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generic:
brand:
None (85) · Delysid (historical, Sandoz, withdrawn 1965) (1) · Temovate, Clobex, Cormax, Olux, Olux-E, Impoyz (1)
classes: (Click arrow to add another value)
mechanism:
5-HT2A agonist (26) · Potent 5-HT2A agonist (5) · LSD analogue; 5-HT2A agonist (4) · Prodrug of LSD; 5-HT2A agonist (4) · Contains LSA (2) · Contains mescaline (2)
uses:
None (86) · '"`UNIQ--vote-0000079C-QINU`"', '"`UNIQ--vote-0000079D-QINU`"' (1)
starting dose:
None (86) · Apply a thin film to affected area BID; '''limit to 2 weeks''' continuous use and ≤50 g/week (cream/ointment); ≤50 mL/week (foam/solution); avoid face, intertriginous areas (1)
preparations:
None (86) · Cream, ointment, lotion, foam, solution, shampoo, spray at 0.025-0.05%; emollient and non-emollient bases (1)
fda max:
None (86) · 50 g/week (cream/ointment); 2-week continuous limit; 4-week maximum cumulative (1)
routes:
None (85) · Oral (1) · Topical (1)
onset:
None (85) · 30–60 minutes (1) · Hours to days for inflammation; substantial improvement within 1 week (1)
duration:
None (85) · 8–12 hours (1) · Hours to days per application (1)
halflife:
None (85) · 3–5 hours (1) · Not meaningfully described for topical use (systemic exposure varies with surface area, occlusion, skin integrity)'"`UNIQ--ref-0000079E-QINU`"' (1)
bioavailability:
None (85) · 70–90% (oral) (1) · Topical with variable systemic absorption depending on body site, occlusion, and skin integrity; HPA-axis suppression is documented even with brief courses to large areas'"`UNIQ--ref-0000079F-QINU`"' (1)
pregnancy:
None (85) · Not established (1) · Topical corticosteroids in pregnancy: use lowest potency and smallest area; super-potent agents like clobetasol are reserved for compelling indications.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
None (85) · Schedule I (United States) (1) · [[USLegal:Prescription only|Rx-only]] in US (1)

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