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Medicines > classes : Botanical or Stimulant or [[:Category:NSAIDs|NSAID (aspirin)]]

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generic:
brand:
None (65) · Benzedrex (1) · Fiorinal; with codeine as Fiorinal with Codeine (Schedule III) (1) · Percodan (1)
classes: (Click arrow to add another value)
mechanism:
Monoamine releasing agent (8) · Dopamine/norepinephrine reuptake inhibitor (5) · Cathinone analogue; monoamine reuptake inhibitor (2) · Contains LSA (2) · Contains mescaline (2) · Dopamine and norepinephrine reuptake inhibitor (2) · Norepinephrine–dopamine reuptake inhibitor (2)
uses:
None (66) · '"`UNIQ--vote-000014F9-QINU`"' (1) · '"`UNIQ--vote-000015B6-QINU`"' (1)
starting dose:
None (66) · 1 tablet (4.8355 mg oxycodone / 325 mg aspirin) PO every 6 hours as needed (1) · 1-2 capsules (50 mg butalbital / 325 mg aspirin / 40 mg caffeine each) PO every 4 hours as needed; maximum 6 capsules/d (1)
preparations:
None (66) · 4.8355 mg oxycodone / 325 mg aspirin tablets (1) · 50/325/40 mg capsules (1)
fda max:
None (66) · 6 capsules/d (300 mg butalbital, 1950 mg aspirin, 240 mg caffeine) (1) · Aspirin GI/bleeding-limited; oxycodone titrated to effect (1)
routes:
None (66) · Oral (2)
onset:
None (66) · 15-30 minutes (1) · 30-60 minutes (1)
duration:
None (66) · 4-6 hours (2)
halflife:
None (66) · Butalbital ~35 hours; aspirin (acetyl group) ~15 minutes, salicylate 2-3 hours; caffeine 3-7 hours'"`UNIQ--ref-000015B7-QINU`"' (1) · Oxycodone 3-5 hours; aspirin (acetyl group) 15-20 minutes, salicylate 2-3 hours at therapeutic doses'"`UNIQ--ref-000014FA-QINU`"' (1)
bioavailability:
None (66) · Butalbital well-absorbed; aspirin 50-75%; caffeine ~100%'"`UNIQ--ref-000015B8-QINU`"' (1) · Oxycodone 60-87%; aspirin 50-75%'"`UNIQ--ref-000014FB-QINU`"' (1)
pregnancy:
None (66) · Avoid; aspirin teratogenicity concerns plus opioid neonatal withdrawal.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1) · Avoided; barbiturate + aspirin teratogenicity and bleeding concerns.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
None (66) · [[USLegal:Schedule III|Schedule III controlled substance]] in US (Fiorinal is scheduled federally; Fioricet with acetaminophen is unscheduled federally despite identical butalbital content, a regulatory quirk) (1) · [[USLegal:Schedule II|Schedule II controlled substance]] in US (1)

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