Jump to content

Drilldown: Medicines

Choose a table:


Medicines > classes : Cardioselective (β1) or Classic Psychedelic or Sedative-Hypnotic

Use the filters below to narrow your results.

generic:
brand:
None (78) · (none, never marketed) (1) · Dalmane (1) · Delysid (historical, Sandoz, withdrawn 1965) (1) · Doral (1) · Doriden (1) · Halcion (1) · Hetlioz (1) · Imovane (1) · Lopressor (tartrate), Toprol XL (succinate) (1) · Lunesta (1) · Mogadon (1) · Nembutal (1) · Placidyl (1) · ProSom (1) · Quaalude (1) · Restoril (1) · Rohypnol (1) · Rozerem (1) · Seconal (1) · Sonata (1) · THIP (1) · Versed (1) · Xyrem (1) · Zebeta (1)
classes: (Click arrow to add another value)
mechanism:
5-HT2A agonist (26) · GABAA positive allosteric modulator (15) · Potent 5-HT2A agonist (5) · LSD analogue; 5-HT2A agonist (4) · Prodrug of LSD; 5-HT2A agonist (4) · GABAA positive allosteric modulator (non-benzodiazepine) (3) · None (2) · Contains LSA (2) · Contains mescaline (2) · GABAA potentiator and direct activator (2) · Melatonin receptor agonist (2)
uses:
None (99) · No approved medical problem. Encountered as a designer/research benzodiazepine and, increasingly, as an adulterant in illicit opioid supplies. (1) · '"`UNIQ--vote-000004F5-QINU`"', '"`UNIQ--vote-000004F6-QINU`"', '"`UNIQ--vote-000004F7-QINU`"', '"`UNIQ--vote-000004F8-QINU`"', '"`UNIQ--vote-000004F9-QINU`"' (1) · '"`UNIQ--vote-00000636-QINU`"', '"`UNIQ--vote-00000637-QINU`"', '"`UNIQ--vote-00000638-QINU`"' (1)
starting dose:
None (99) · 2.5–5 mg daily (HTN); 1.25 mg daily (HFrEF, slow titration) (1) · 25–50 mg BID (tartrate); 25–100 mg daily (succinate); 12.5 mg daily in HFrEF (1) · No medical dose. Active recreational doses reported in the 0.5–1.5 mg range (similar potency to alprazolam). (1)
preparations:
None (99) · 5, 10 mg tabs (1) · Illicit tablets ("bars"), powders, blotter, occasionally solutions. No pharmaceutical product exists. (1) · Tartrate: 25, 50, 100 mg tabs; 1 mg/mL IV. Succinate ER: 25, 50, 100, 200 mg. (1)
fda max:
None (99) · 20 mg/d (1) · 400 mg/d (1) · N/A (never approved) (1)
routes:
None (98) · intranasal; rectal and IV reported. (1) · IV (1) · Oral (4) · sublingual (1)
onset:
None (98) · 1–2 h (1) · 1–2 h (PO); immediate (IV) (1) · 30–60 minutes (1) · ~20–40 min PO; faster sublingual/intranasal. (1)
duration:
None (98) · 24 h (1) · 6–10 h subjective; full pharmacologic effect considerably longer. (1) · 6–12 h (tartrate); 24 h (succinate) (1) · 8–12 hours (1)
halflife:
None (98) · 3–5 hours (1) · 3–7 h (1) · 9–12 h (1) · Estimated ~12–17 h (some sources cite up to ~21 h); active metabolites prolong effect. (1)
bioavailability:
None (98) · 70–90% (oral) (1) · Not formally characterized in humans. (1) · ~50% (1) · ~90% (low first-pass) (1)
pregnancy:
None (98) · Avoid. Benzodiazepines are associated with neonatal sedation, floppy-infant syndrome, and withdrawal; teratogenic signal weak but non-zero. Designer benzo with no safety data, assume worst-case. (1) · Category C (2) · Not established (1)
legal:
None (99) · Rx-only in US (2) · Schedule I (United States) (1)

Showing below up to 102 results in range #1 to #102.

View (previous 250 | next 250) (20 | 50 | 100 | 250 | 500)


View (previous 250 | next 250) (20 | 50 | 100 | 250 | 500)

Retrieved from "https://pharmacopedia.wiki/p/Special:Drilldown/Medicines"