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Medicines > classes : Cathinone or [[:Category:Calcium_channel_blockers|Calcium channel blocker]]

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generic:
3-MMC (1) · Amlodipine (1) · Butylone (1) · Cathinone (1) · Ephylone (1) · Ethcathinone (1) · Ethylone (1) · Hexedrone (1) · Mephedrone (1) · Methcathinone (1) · Methylone (1) · Mexedrone (1) · N-Ethylhexedrone (1) · N-Ethylpentedrone (1) · Pentedrone (1)
brand:
None (14) · Norvasc, Katerzia (1)
classes: (Click arrow to add another value)
mechanism:
Cathinone analogue; monoamine reuptake inhibitor (2) · Monoamine releasing agent (4) · Monoamine releasing agent; active ingredient in khat (1) · Norepinephrine and dopamine releasing agent (1) · Norepinephrine/dopamine releasing agent (1) · Norepinephrine/dopamine reuptake inhibitor (1) · Serotonin releasing agent; monoamine reuptake inhibitor (1) · Serotonin/norepinephrine/dopamine releasing agent (3) · '"`UNIQ--vote-00000073-QINU`"' The long half-life gives smooth, once-daily BP control with low rebound. CYP3A4 substrate; pedal edema is the characteristic, dose-related, non-fluid-overload side effect'"`UNIQ--ref-00000074-QINU`"'. (1)
uses:
None (14) · '"`UNIQ--vote-00000075-QINU`"', '"`UNIQ--vote-00000076-QINU`"', '"`UNIQ--vote-00000077-QINU`"' (1)
starting dose:
None (14) · 2.5-5 mg PO once daily; titrate to 10 mg/d (1)
preparations:
None (14) · 2.5, 5, 10 mg tablets; 1 mg/mL oral suspension (1)
fda max:
None (14) · 10 mg/d (1)
routes:
None (14) · Oral (1)
onset:
None (14) · BP effect within 24 hours; full effect at 1-2 weeks (long half-life) (1)
duration:
None (14) · 24 hours (1)
halflife:
None (14) · 30-50 hours'"`UNIQ--ref-00000078-QINU`"' (1)
bioavailability:
None (14) · 64-90% (oral; not affected by food)'"`UNIQ--ref-00000079-QINU`"' (1)
pregnancy:
None (14) · Limited data; case series and registries suggest no major teratogenicity but other antihypertensives (labetalol, nifedipine) are typically preferred.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
None (14) · [[USLegal:Prescription only|Rx-only]] in US (1)

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