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Medicines > classes : Cathinone or Classic Psychedelic or [[:Category:Macrocyclic_lactones|Macrocyclic lactone (avermectin)]]

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generic:
brand:
None (83) · Delysid (historical, Sandoz, withdrawn 1965) (1) · Stromectol (oral, generic), Sklice (lice, topical), Soolantra (rosacea, topical 1%) (1)
classes: (Click arrow to add another value)
mechanism:
5-HT2A agonist (26) · Potent 5-HT2A agonist (5) · LSD analogue; 5-HT2A agonist (4) · Monoamine releasing agent (4) · Prodrug of LSD; 5-HT2A agonist (4) · Serotonin/norepinephrine/dopamine releasing agent (3) · Cathinone analogue; monoamine reuptake inhibitor (2) · Contains LSA (2) · Contains mescaline (2)
uses:
None (84) · '"`UNIQ--vote-0000108C-QINU`"', '"`UNIQ--vote-0000108D-QINU`"', '"`UNIQ--vote-0000108E-QINU`"', '"`UNIQ--vote-0000108F-QINU`"', '"`UNIQ--vote-00001090-QINU`"', '"`UNIQ--vote-00001091-QINU`"' (1)
starting dose:
None (84) · Strongyloides 200 mcg/kg PO single dose; scabies 200 mcg/kg PO repeated at 7-14 days; onchocerciasis 150 mcg/kg q6-12 months (1)
preparations:
None (84) · 3 mg tablets (Stromectol); 0.5% topical lotion (Sklice); 1% topical cream (Soolantra) (1)
fda max:
None (84) · Single 200-400 mcg/kg per dose for systemic indications (1)
routes:
None (83) · Oral (2) · topical (1)
onset:
None (83) · 30–60 minutes (1) · Hours to days (1)
duration:
None (83) · 8–12 hours (1) · Variable (1)
halflife:
None (83) · 3–5 hours (1) · ~16-18 hours'"`UNIQ--ref-00001092-QINU`"' (1)
bioavailability:
None (83) · 70–90% (oral) (1) · ~60% (oral; substantially increased with high-fat meal)'"`UNIQ--ref-00001093-QINU`"' (1)
pregnancy:
None (83) · Limited data; risk-benefit case by case; pregnancy is not a strict contraindication in WHO mass drug administration programs.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1) · Not established (1)
legal:
None (83) · Schedule I (United States) (1) · [[USLegal:Prescription only|Rx-only]] in US (the veterinary preparations are not for human use) (1)

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