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Drilldown: Medicines

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Medicines > classes : Cathinone or Classic Psychedelic or SSRI)]]

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generic:
brand:
None (83) · Delysid (historical, Sandoz, withdrawn 1965) (1) · Symbyax (1)
classes: (Click arrow to add another value)
mechanism:
5-HT2A agonist (26) · Potent 5-HT2A agonist (5) · LSD analogue; 5-HT2A agonist (4) · Monoamine releasing agent (4) · Prodrug of LSD; 5-HT2A agonist (4) · Serotonin/norepinephrine/dopamine releasing agent (3) · Cathinone analogue; monoamine reuptake inhibitor (2) · Contains LSA (2) · Contains mescaline (2)
uses:
None (84) · '"`UNIQ--vote-0000154B-QINU`"', '"`UNIQ--vote-0000154C-QINU`"' (1)
starting dose:
None (84) · 6/25 mg PO once daily in the evening; titrate within range 3/25 to 18/75 mg by clinical response and tolerability (1)
preparations:
None (84) · Capsules: 3/25, 6/25, 6/50, 12/25, 12/50 mg olanzapine/fluoxetine (1)
fda max:
None (84) · 18 mg olanzapine / 75 mg fluoxetine per day (1)
routes:
None (83) · Oral (2)
onset:
None (83) · 30–60 minutes (1) · Mood improvement at 1-3 weeks; full effect 4-6 weeks (1)
duration:
None (83) · 24 hours (1) · 8–12 hours (1)
halflife:
None (83) · 3–5 hours (1) · Olanzapine ~30 hours; fluoxetine 1-4 days (norfluoxetine 7-15 days)'"`UNIQ--ref-0000154D-QINU`"' (1)
bioavailability:
None (83) · 70–90% (oral) (1) · Olanzapine 60% (oral); fluoxetine high (oral)'"`UNIQ--ref-0000154E-QINU`"' (1)
pregnancy:
None (83) · Limited data; fluoxetine has reassuring data but olanzapine carries metabolic-syndrome and gestational diabetes signals.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1) · Not established (1)
legal:
None (83) · Schedule I (United States) (1) · [[USLegal:Prescription only|Rx-only]] in US. Carries the '''antidepressant Boxed Warning''' for suicidality in children/adolescents/young adults and the atypical-neuroleptic '''Boxed Warning''' for increased mortality in elderly dementia patients'"`UNIQ--ref-0000154F-QINU`"' (1)

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