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Drilldown: Medicines

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Medicines > classes : Cathinone or preferential COX-2)]]

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generic:
3-MMC (1) · Butylone (1) · Cathinone (1) · Ephylone (1) · Ethcathinone (1) · Ethylone (1) · Hexedrone (1) · Meloxicam (1) · Mephedrone (1) · Methcathinone (1) · Methylone (1) · Mexedrone (1) · N-Ethylhexedrone (1) · N-Ethylpentedrone (1) · Pentedrone (1)
brand:
None (14) · Mobic, Vivlodex (lower-dose capsules), Anjeso (IV) (1)
classes: (Click arrow to add another value)
mechanism:
Cathinone analogue; monoamine reuptake inhibitor (2) · Monoamine releasing agent (4) · Monoamine releasing agent; active ingredient in khat (1) · Norepinephrine and dopamine releasing agent (1) · Norepinephrine/dopamine releasing agent (1) · Norepinephrine/dopamine reuptake inhibitor (1) · Serotonin releasing agent; monoamine reuptake inhibitor (1) · Serotonin/norepinephrine/dopamine releasing agent (3) · '"`UNIQ--vote-00000019-QINU`"' Once-daily dosing is a clinical advantage over short-half-life NSAIDs'"`UNIQ--ref-0000001A-QINU`"'. (1)
uses:
None (14) · '"`UNIQ--vote-0000001B-QINU`"', '"`UNIQ--vote-0000001C-QINU`"', '"`UNIQ--vote-0000001D-QINU`"', '"`UNIQ--vote-0000001E-QINU`"', '"`UNIQ--vote-0000001F-QINU`"' (1)
starting dose:
None (14) · 7.5 mg PO once daily; titrate to 15 mg daily if needed. Vivlodex 5 mg PO once daily, max 10 mg (1)
preparations:
None (14) · Tablets 7.5, 15 mg (Mobic); capsules 5, 10 mg (Vivlodex); oral suspension 7.5 mg/5 mL; injection 30 mg/mL (Anjeso) (1)
fda max:
None (14) · 15 mg/day (oral); 30 mg IV once daily (Anjeso) (1)
routes:
None (14) · intravenous (1) · Oral (1)
onset:
None (14) · Analgesic effect within hours; full anti-inflammatory effect over 1-2 weeks (1)
duration:
None (14) · 24 hours (once-daily dosing supported by long half-life) (1)
halflife:
None (14) · 15-20 hours'"`UNIQ--ref-00000020-QINU`"' (1)
bioavailability:
None (14) · ~89% (oral)'"`UNIQ--ref-00000021-QINU`"' (1)
pregnancy:
None (14) · Avoid from 20 weeks gestation onward per FDA's 2020 expanded NSAID warning (fetal renal dysfunction, oligohydramnios); contraindicated from 30 weeks (risk of premature ductus arteriosus closure)'"`UNIQ--ref-00000022-QINU`"' (1)
legal:
None (14) · [[USLegal:Prescription only|Rx-only]] in US (1)

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