Drilldown: Medicines
Use the filters below to narrow your results.
generic:
brand:
classes: (Click arrow to add another value)
mechanism:
uses:
starting dose:
preparations:
onset:
None (88) ·
30–60 minutes (1) ·
Peak plasma concentration in 2-4 hours after oral administration. Clinically perceptible wakefulness-promoting effects typically begin within 1-2 hours of dosing.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> (1) ·
Within hours of first administration (1)
duration:
None (88) ·
8–12 hours (1) ·
Acute effect ~24 hours; cumulative effect builds with repeated dosing (1) ·
Effective duration approximately 12-15 hours at the 200 mg dose, consistent with the elimination half-life. A single morning dose generally sustains wakefulness throughout the day without substantially disrupting nighttime sleep onset when taken early.'"`UNIQ--ref-0000006D-QINU`"' (1)
halflife:
bioavailability:
None (88) ·
70–90% (oral) (1) ·
Oral bioavailability is not precisely established in the label but absorption is rapid and essentially complete. Food delays peak plasma concentration by approximately one hour but does not reduce the extent of absorption.'"`UNIQ--ref-0000006F-QINU`"' (1) ·
~48% intranasal (1)
pregnancy:
Showing below up to 91 results in range #1 to #91.